Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | POLA1 | P09884 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | POLG | P54098 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGAV | P06756 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25416162 | 0.81 | LMNA (0.39) | PDE3APDE4DSLC29A1LMNACACNA1F | |
| SCHEMBL20165892 | 0.80 | PDE3A (0.42) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL20213099 | 0.80 | PDE3A (0.42) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL2889211 | 0.79 | PDE3A (0.36) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL20213226 | 0.78 | PDE3A (0.44) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL18263767 | 0.78 | PDE3A (0.46) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL20213094 | 0.78 | PDE3A (0.46) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL18263819 | 0.78 | PDE3A (0.46) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL20549183 | 0.75 | LMNA (0.33) | PDE3APDE4DSLC29A1LMNACACNA1F | |
| SCHEMBL15880881 | 0.75 | CYP3A4 (0.40) | SLC29A1POLA1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081105-A1 | CYCLIC PHOSPHORAMIDATE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2023-05-11 | — | — | WO | disclosed |