Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.39 |
| ▸ | POLG | P54098 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.32 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.32 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25416263 | 0.81 | PDE3A (0.43) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL20549183 | 0.77 | LMNA (0.33) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL25439028 | 0.77 | STING1 (0.45) | — | |
| SCHEMBL25416164 | 0.76 | LMNA (0.39) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL23610454 | 0.73 | LMNA (0.38) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL22589431 | 0.71 | FGFR1 (0.40) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL2889211 | 0.71 | PDE3A (0.36) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL25414623 | 0.68 | MEN1 (0.36) | — | |
| SCHEMBL21257902 | 0.67 | CACNA1F (0.31) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL8622800 | 0.67 | LMNA (0.40) | LMNAPDE3ACACNA1FALBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081105-A1 | CYCLIC PHOSPHORAMIDATE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2023-05-11 | — | — | WO | disclosed |