Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21584536 | 0.77 | PDE4B (0.32) | NPC1RAB9APDE4B | |
| SCHEMBL21584712 | 0.74 | NPC1 (0.36) | NPC1RAB9AHCRTR1CASP3SENP8 | |
| SCHEMBL24529390 | 0.69 | NPC1 (0.33) | NPC1RAB9AHCRTR1CASP3SENP8 | |
| SCHEMBL7947758 | 0.68 | ENPP3 (0.39) | NPC1RAB9ALMNACYP1A2KDM4E | |
| SCHEMBL18632452 | 0.65 | AHR (0.39) | NPC1RAB9ATSHRHCRTR1CASP3 | |
| SCHEMBL4035386 | 0.65 | AHR (0.35) | NPC1RAB9ATSHRHCRTR1CASP3 | |
| SCHEMBL4099999 | 0.64 | PIK3CG (0.41) | NPC1RAB9ATSHRPIK3CGRECQL | |
| SCHEMBL26857578 | 0.63 | PIK3CG (0.49) | NPC1RAB9AHCRTR1CASP3SENP8 | |
| SCHEMBL17629354 | 0.62 | TSHR (0.53) | TSHRLMNARECQLCYP1A2HTT | |
| SCHEMBL20602282 | 0.61 | AHR (0.40) | NPC1RAB9ATSHRLMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250026753-A1 | FUSED TRIAZINONE DERIVATIVES AND METHODS OF USING THE SAME | RGENTA THERAPEUTICS, INC. | 2025-01-23 | — | — | US | disclosed |
| WO-2024238793-A1 | FUSED TRIAZINONES FOR USE IN THE TREATMENT OF CANCER | RGENTA THERAPEUTICS, INC. (US) | 2024-11-21 | — | — | WO | disclosed |
| CN-118871445-A | Fused triazinone derivatives and methods of use thereof | 亚根达医疗公司 | 2024-10-29 | — | — | CN | disclosed |
| WO-2023086959-A1 | FUSED TRIAZINONE DERIVATIVES AND METHODS OF USING THE SAME | RGENTA THERAPEUTICS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| WO-2023086959-A1 | FUSED TRIAZINONE DERIVATIVES AND METHODS OF USING THE SAME | RGENTA THERAPEUTICS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250026753-A1 | FUSED TRIAZINONE DERIVATIVES AND METHODS OF USING THE SAME | SF3B5, RBM17, SF3A2 | NPC1 992/4885RAB9A 3009/4885TSHR 2427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.