Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28452549 | 0.89 | LOXL2 (0.56) | CA1CA2CA12CA7CA9 | |
| SCHEMBL8351056 | 0.85 | TSHR (0.60) | CA1CA2CA12CA7CA9 | |
| SCHEMBL16758244 | 0.85 | CA1 (0.57) | CA1CA2CA12CA7CA9 | |
| SCHEMBL9279020 | 0.84 | LMNA (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL28993944 | 0.83 | CA1 (0.80) | CA1CA2CA12CA7CA9 | |
| SCHEMBL23600 | 0.83 | CA1 (0.80) | CA1CA2CA12CA7CA9 | |
| Methyl Alcohol SCHEMBL28561085 | 0.81 | CA1 (0.76) | CA1CA2CA12CA7CA9 | |
| SCHEMBL28704033 | 0.81 | CA1 (0.76) | CA1CA2CA12CA7CA9 | |
| Water SCHEMBL22720573 | 0.81 | CA1 (0.76) | CA1CA2CA12CA7CA9 | |
| SCHEMBL28531063 | 0.81 | CA1 (0.76) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150284849-A1 | LOW-K FILMS WITH ENHANCED CROSSLINKING BY UV CURING | APPLIED MATERIALS, INC. (US) | 2015-10-08 | — | — | US | disclosed |
| US-20150284849-A1 | LOW-K FILMS WITH ENHANCED CROSSLINKING BY UV CURING | APPLIED MATERIALS, INC. (US) | 2015-10-08 | — | — | US | disclosed |
| US-20130065248-A1 | REAGENTS AND METHODS FOR SIRTUIN CAPTURE | CORNELL UNIVERSITY (US) | 2013-03-14 | — | — | US | disclosed |
| WO-2012031298-A2 | ETHYNYLBENZENE DERIVATIVES | DUKE UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |
| US-20090023734-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2009-01-22 | — | — | US | disclosed |
| US-7282608-B2 | Inhibitors of histone deacetylase | METHYLGENE, INC. (CA) | 2007-10-16 | — | — | US | disclosed |
| US-5141932-A | Antitumor agents | SANDOZ PHARMACEUTICALS CORP. (US) | 1992-08-25 | — | — | US | disclosed |
| US-4992428-A | Hypotensive agents, antiallergens, bronchodilator | SANDOZ PHARM. CORP. (US) | 1991-02-12 | — | — | US | disclosed |
| US-4910206-A | Endotoxin induced lung injury | SANDOZ PHARMACEUTICALS CORP. (US) | 1990-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023734-A1 | INHIBITORS OF HISTONE DEACETYLASE | HDAC1, HDAC11, HDAC6 | CA1 2287/4885CA2 1762/4885CA12 2624/4885 |
| US-20130065248-A1 | REAGENTS AND METHODS FOR SIRTUIN CAPTURE | SIRT3, SIRT1, SIRT2 | CA1 2867/4885CA2 2770/4885CA12 2350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.