Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 11/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | TEC | P42680 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25423645 | 0.74 | BTK (0.46) | BTKEGFR | |
| SCHEMBL19909712 | 0.73 | ALDH1A1 (0.65) | BTKALDH1A1LMNATDP1 | |
| SCHEMBL19909686 | 0.72 | ALDH1A1 (0.63) | BTKSCN9AALDH1A1TDP1 | |
| SCHEMBL20998572 | 0.71 | BTK (0.72) | BTKEGFRTEC | |
| SCHEMBL16597779 | 0.70 | BTK (0.71) | BTKEGFRTECSCN9ACHEK2 | |
| SCHEMBL16597947 | 0.70 | BTK (0.70) | BTKEGFRTECSCN9ACHEK2 | |
| SCHEMBL16597594 | 0.70 | BTK (0.71) | BTKEGFRTECSCN9A | |
| SCHEMBL22212893 | 0.69 | SCN9A (0.51) | BTKEGFRTECSCN9ACHEK2 | |
| SCHEMBL16597863 | 0.69 | BTK (0.55) | BTKEGFRTECSCN9ACHEK2 | |
| SCHEMBL25649417 | 0.69 | BTK (0.55) | BTKEGFRTECSCN9ACHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |