Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25259649 | 0.84 | HTR6 (0.41) | KMT2AGPR119MEN1L3MBTL1MAPT | |
| SCHEMBL30381756 | 0.73 | CD4 (0.44) | SMN1; SMN2GAAALDH1A1L3MBTL1LMNA | |
| SCHEMBL25257908 | 0.73 | CD4 (0.44) | SMN1; SMN2GAAALDH1A1L3MBTL1LMNA | |
| SCHEMBL25424441 | 0.72 | NPSR1 (0.37) | KMT2ASMN1; SMN2PKMNPSR1MEN1 | |
| SCHEMBL3797631 | 0.69 | KDM4E (0.51) | KMT2AGAAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL30381434 | 0.68 | HTR6 (0.39) | KMT2AGPR119MEN1MAPT | |
| SCHEMBL25304050 | 0.68 | HTR6 (0.39) | KMT2AGPR119MEN1MAPT | |
| SCHEMBL31212490 | 0.68 | JAK1 (0.40) | KMT2AGAAALDH1A1L3MBTL1LMNA | |
| SCHEMBL1934659 | 0.68 | L3MBTL1 (0.45) | KMT2APKMGAAALDH1A1L3MBTL1 | |
| SCHEMBL1933804 | 0.67 | KDM4E (0.49) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107723-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |