Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CD4 | P01730 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25439518 | 0.82 | ALDH1A1 (0.36) | NPSR1CD4ALDH1A1GAALMNA | |
| SCHEMBL25427425 | 0.77 | ALDH1A1 (0.37) | NPSR1ALDH1A1GAALMNAUSP2 | |
| SCHEMBL30381641 | 0.77 | ALDH1A1 (0.37) | NPSR1ALDH1A1GAALMNAUSP2 | |
| SCHEMBL25428681 | 0.73 | ALDH1A1 (0.39) | ALDH1A1GAALMNAUSP2SMN1; SMN2 | |
| SCHEMBL30381550 | 0.73 | ALDH1A1 (0.39) | ALDH1A1GAALMNAUSP2SMN1; SMN2 | |
| SCHEMBL30381434 | 0.72 | HTR6 (0.39) | KMT2AMEN1HTR6ESR2 | |
| SCHEMBL25304050 | 0.72 | HTR6 (0.39) | KMT2AMEN1HTR6ESR2 | |
| SCHEMBL25424437 | 0.72 | KMT2A (0.40) | NPSR1ALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL25427656 | 0.71 | PTPN11 (0.39) | ALDH1A1GAALMNAUSP2SMN1; SMN2 | |
| SCHEMBL30381664 | 0.71 | PTPN11 (0.39) | ALDH1A1GAALMNAUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107723-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |