Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.79 |
| ▸ | MAOA | P21397 | 4/20 | 0.79 |
| ▸ | TYR | P14679 | 2/20 | 0.79 |
| ▸ | MEN1 | O00255 | 6/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | RECQL | P46063 | 2/20 | 0.67 |
| ▸ | STK17B | O94768 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.67 |
| ▸ | AURKA | O14965 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.67 |
| ▸ | JAK2 | O60674 | 1/20 | 0.67 |
| ▸ | ALPL | P05186 | 1/20 | 0.67 |
| ▸ | ALPI | P09923 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | ALPG | P10696 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5707772 | 0.92 | MAOB (0.83) | MAOBMAOATYRMEN1KMT2A | |
| SCHEMBL5707779 | 0.92 | MAOB (0.83) | MAOBMAOATYRMEN1KMT2A | |
| SCHEMBL29435856 | 0.89 | TYR (1.00) | MAOBMAOATYRMEN1KMT2A | |
| SCHEMBL5707753 | 0.89 | TYR (1.00) | MAOBMAOATYRMEN1KMT2A | |
| SCHEMBL30214422 | 0.89 | TYR (1.00) | MAOBMAOATYRMEN1KMT2A | |
| SCHEMBL30214414 | 0.85 | TYR (0.86) | MAOBMAOATYRMEN1KMT2A | |
| SCHEMBL28949991 | 0.85 | TYR (0.86) | MAOBMAOATYRMEN1KMT2A | |
| SCHEMBL21046449 | 0.83 | MEN1 (1.00) | MAOBMAOATYRMEN1KMT2A | |
| 6-Hydroxy-4'-Chloro Aurone SCHEMBL30214387 | 0.83 | ELANE (0.88) | MAOBMAOATYRMEN1KMT2A | |
| SCHEMBL19462969 | 0.83 | MAOA (0.83) | MAOBMAOATYRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114761-A2 | TARGETING ERO1 ALPHA WITH AURONE DERIVATIVES | West Virginia University Board of Governors on behalf of West Virginia University (US) | 2023-06-22 | — | — | WO | disclosed |