SCHEMBL29435856

SCHEMBL29435856

O=C1/C(=C/c2ccc(O)cc2)Oc2cc(O)ccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TYR P14679 4/20 1.00
▸ MAOA P21397 3/20 1.00
▸ MAOB P27338 3/20 1.00
▸ MEN1 O00255 7/20 0.83
▸ KMT2A Q03164 7/20 0.83
▸ POLB P06746 2/20 0.83
▸ RAB9A P51151 2/20 0.83
▸ RECQL P46063 3/20 0.78
▸ STK17B O94768 2/20 0.78
▸ KDM4E B2RXH2 2/20 0.78
▸ NPC1 O15118 2/20 0.78
▸ GAA P10253 2/20 0.78
▸ MAPT P10636 2/20 0.78
▸ PSMD14 O00487 1/20 0.78
▸ AURKA O14965 1/20 0.78
▸ DAPK3 O43293 1/20 0.78
▸ JAK2 O60674 1/20 0.78
▸ ALPL P05186 1/20 0.78
▸ ALPI P09923 1/20 0.78
▸ ALPG P10696 1/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5707753 1.00 TYR (1.00) TYRMAOAMAOBMEN1KMT2A
SCHEMBL30214422 1.00 TYR (1.00) TYRMAOAMAOBMEN1KMT2A
SCHEMBL30214414 0.92 TYR (0.86) TYRMAOAMAOBMEN1KMT2A
SCHEMBL28949991 0.92 TYR (0.86) TYRMAOAMAOBMEN1KMT2A
SCHEMBL30214416 0.91 MAOB (0.83) TYRMAOAMAOBMEN1KMT2A
SCHEMBL30214402 0.91 MAOB (0.83) TYRMAOAMAOBMEN1KMT2A
6-Hydroxy-4'-Chloro Aurone SCHEMBL30214415 0.91 ELANE (0.88) TYRMAOAMAOBMEN1KMT2A
SCHEMBL19462969 0.91 MAOA (0.83) TYRMAOAMAOBMEN1KMT2A
SCHEMBL21046449 0.91 MEN1 (1.00) TYRMAOAMAOBMEN1KMT2A
6-Hydroxy-4'-Chloro Aurone SCHEMBL30214387 0.91 ELANE (0.88) TYRMAOAMAOBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677635-A Aurone derivative and application thereof 中国科学院新疆理化技术研究所 2023-02-03 — — CN claimed
US-12569530-B2 Tannin-based antiproliferative pharmaceutical IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2026-03-10 — — US disclosed
CN-121550211-A Application of compound Hispidol or pharmaceutically acceptable salt thereof in preparation of lipophage activator 上海临港同济大学智慧科技研究院 2026-02-24 — — CN disclosed
CN-121550211-A Application of compound Hispidol or pharmaceutically acceptable salt thereof in preparation of lipophage activator 上海临港同济大学智慧科技研究院 2026-02-24 — — CN disclosed
US-12507703-B2 Methods, devices and compositions for preserving human milk THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-12-30 — — US disclosed
US-12453799-B1 Bioadhesive for medical and dental applications IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) 2025-10-28 — — US disclosed
US-20250249063-A1 METHOD FOR TREATING ORAL CANCER IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2025-08-07 — — US disclosed
US-12318422-B2 Tannin-based antiproliferative pharmaceutical IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2025-06-03 — — US disclosed
US-20250169516-A1 METHODS, DEVICES AND COMPOSITIONS FOR PRESERVING HUMAN MILK THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-05-29 — — US disclosed
CN-119639835-A Preparation method of keemun camellia seed fermented oil 广州中妆美业化妆品有限公司 2025-03-18 — — CN disclosed
US-20240268402-A1 Methods, Devices and Compositions for Preserving Human Milk THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2024-08-15 — — US disclosed
CN-115677635-B Orange ketone derivative and application thereof 中国科学院新疆理化技术研究所 2024-04-09 — — CN disclosed
US-20230295103-A1 AURONE DERIVATIVES AND USES THEREOF FOR CONTROLLING BACTERIA AND/OR FUNGI ECOLE CENTRALE DE MARSEILLE (FR) 2023-09-21 — — US disclosed
US-20230210931-A1 TANNIN-BASED ANTIPROLIFERATIVE PHARMACEUTICAL IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2023-07-06 — — US disclosed
EP-4178952-A2 AURONE DERIVATIVES AND USES THEREOF FOR CONTROLLING BACTERIA AND/OR FUNGI Université d'Aix Marseille (FR) 2023-05-17 — — EP disclosed
CN-115677635-A Aurone derivative and application thereof 中国科学院新疆理化技术研究所 2023-02-03 — — CN disclosed
US-11376570-B1 Method of forming copper oxide-on-copper nanomaterial catalyst mesh KING ABDULAZIZ UNIVERSITY (SA) 2022-07-05 — — US disclosed
US-11311492-B1 Carbon nanomedicine with natural ligands KING ABDULAZIZ UNIVERSITY (SA) 2022-04-26 — — US disclosed
US-11254700-B2 GSK-3β inhibitors and use thereof in methods of treatment UNIVERSITY OF HAWAII (US) 2022-02-22 — — US disclosed
US-11234940-B1 Method for making a noble metal nanomedicine KING ABDULAZIZ UNIVERSITY (SA) 2022-02-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12507703-B2 Methods, devices and compositions for preserving human milk LPL, CEL, LPO TYR 1700/4885MAOA 471/4885MAOB 293/4885
US-20250249063-A1 METHOD FOR TREATING ORAL CANCER UGGT1, G6PD, UGT1A3 TYR 506/4885MAOA 3217/4885MAOB 4135/4885
US-20230295103-A1 AURONE DERIVATIVES AND USES THEREOF FOR CONTROLLING BACTERIA AND/OR FUNGI AURKA, CYP51A1, AURKC TYR 472/4885MAOA 281/4885MAOB 284/4885
US-12569530-B2 Tannin-based antiproliferative pharmaceutical SLC2A3, SLC2A1, SLC2A8 TYR 172/4885MAOA 3606/4885MAOB 4076/4885
US-11254700-B2 GSK-3β inhibitors and use thereof in methods of treatment GSK3B, GSK3A, GSKIP TYR 2809/4885MAOA 2012/4885MAOB 1748/4885
US-20230210931-A1 TANNIN-BASED ANTIPROLIFERATIVE PHARMACEUTICAL UGGT1, G6PD, UGDH TYR 284/4885MAOA 3285/4885MAOB 4088/4885
US-12318422-B2 Tannin-based antiproliferative pharmaceutical UGGT1, G6PD, UGDH TYR 284/4885MAOA 3285/4885MAOB 4088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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