Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 4/20 | 1.00 |
| ▸ | MAOA | P21397 | 3/20 | 1.00 |
| ▸ | MAOB | P27338 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 7/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.83 |
| ▸ | POLB | P06746 | 2/20 | 0.83 |
| ▸ | RAB9A | P51151 | 2/20 | 0.83 |
| ▸ | RECQL | P46063 | 3/20 | 0.78 |
| ▸ | STK17B | O94768 | 2/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.78 |
| ▸ | NPC1 | O15118 | 2/20 | 0.78 |
| ▸ | GAA | P10253 | 2/20 | 0.78 |
| ▸ | MAPT | P10636 | 2/20 | 0.78 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.78 |
| ▸ | AURKA | O14965 | 1/20 | 0.78 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.78 |
| ▸ | JAK2 | O60674 | 1/20 | 0.78 |
| ▸ | ALPL | P05186 | 1/20 | 0.78 |
| ▸ | ALPI | P09923 | 1/20 | 0.78 |
| ▸ | ALPG | P10696 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30214422 | 1.00 | TYR (1.00) | TYRMAOAMAOBMEN1KMT2A | |
| SCHEMBL29435856 | 1.00 | TYR (1.00) | TYRMAOAMAOBMEN1KMT2A | |
| SCHEMBL30214414 | 0.92 | TYR (0.86) | TYRMAOAMAOBMEN1KMT2A | |
| SCHEMBL28949991 | 0.92 | TYR (0.86) | TYRMAOAMAOBMEN1KMT2A | |
| SCHEMBL30214416 | 0.91 | MAOB (0.83) | TYRMAOAMAOBMEN1KMT2A | |
| SCHEMBL30214402 | 0.91 | MAOB (0.83) | TYRMAOAMAOBMEN1KMT2A | |
| 6-Hydroxy-4'-Chloro Aurone SCHEMBL30214415 | 0.91 | ELANE (0.88) | TYRMAOAMAOBMEN1KMT2A | |
| SCHEMBL19462969 | 0.91 | MAOA (0.83) | TYRMAOAMAOBMEN1KMT2A | |
| SCHEMBL21046449 | 0.91 | MEN1 (1.00) | TYRMAOAMAOBMEN1KMT2A | |
| 6-Hydroxy-4'-Chloro Aurone SCHEMBL30214387 | 0.91 | ELANE (0.88) | TYRMAOAMAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060228313-A1 | Method of cosmetic depigmentation care by applying at least one aurone | COLETICA (FR) | 2006-10-12 | — | — | US | claimed |
| EP-1709964-A2 | A method of cosmetic depigmentation care by applying at least one aurone | ENGELHARD LYON (FR) | 2006-10-11 | — | — | EP | claimed |
| US-11254700-B2 | GSK-3β inhibitors and use thereof in methods of treatment | UNIVERSITY OF HAWAII (US) | 2022-02-22 | — | — | US | disclosed |
| US-20200331948-A1 | GSK-3ß INHIBITORS AND USE THEREOF IN METHODS OF TREATMENT | UNIVERSITY OF HAWAII (US) | 2020-10-22 | — | — | US | disclosed |
| WO-2010110647-A1 | AURONES AS ESTROGEN RECEPTOR MODULATORS AND THEIR USE IN SEX HORMONE DEPENDENT DISEASES | BIOTROPICS MALAYSIA BERHAD (MY) | 2010-09-30 | — | — | WO | disclosed |
| US-20060228313-A1 | Method of cosmetic depigmentation care by applying at least one aurone | COLETICA (FR) | 2006-10-12 | — | — | US | disclosed |
| EP-1709964-A2 | A method of cosmetic depigmentation care by applying at least one aurone | ENGELHARD LYON (FR) | 2006-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331948-A1 | GSK-3ß INHIBITORS AND USE THEREOF IN METHODS OF TREATMENT | GSK3B, GSK3A, GSKIP | TYR 3102/4885MAOA 1977/4885MAOB 1651/4885 |
| US-20060228313-A1 | Method of cosmetic depigmentation care by applying at least one aurone | TYR, MITF, MC1R | TYR 1/4885MAOA 23/4885MAOB 27/4885 |
| US-11254700-B2 | GSK-3β inhibitors and use thereof in methods of treatment | GSK3B, GSK3A, GSKIP | TYR 2809/4885MAOA 2012/4885MAOB 1748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.