Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL28321499 | 0.72 | TLR7 (0.44) | TLR7PPARGCNR2KDM4EGLA | |
| SCHEMBL1161593 | 0.68 | GRM2 (0.39) | KCNH2PPARGGRM2KDM4EMAPT | |
| SCHEMBL6756141 | 0.65 | TLR8 (0.56) | TLR7KCNH2ALDH1A1MAPTTLR8 | |
| SCHEMBL6756282 | 0.64 | TLR7 (0.55) | TLR7KCNH2ALDH1A1MAPTTLR8 | |
| SCHEMBL6753996 | 0.64 | TLR7 (0.55) | TLR7KCNH2ALDH1A1MAPTTLR8 | |
| SCHEMBL6753931 | 0.64 | TLR7 (0.55) | TLR7KCNH2ALDH1A1MAPTTLR8 | |
| SCHEMBL6753948 | 0.64 | TLR7 (0.55) | TLR7KCNH2ALDH1A1MAPTTLR8 | |
| SCHEMBL6753962 | 0.64 | TLR7 (0.55) | TLR7KCNH2ALDH1A1MAPTTLR8 | |
| SCHEMBL6759152 | 0.64 | TLR7 (0.55) | TLR7KCNH2ALDH1A1MAPTTLR8 | |
| SCHEMBL6756124 | 0.64 | TLR7 (0.55) | TLR7KCNH2ALDH1A1MAPTTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101243-A1 | SUBSTITUTED BENZAZOLOPORPHYRAZINES FOR POLYMERIZATION AND SURFACE ATTACHMENT AND ARTICLES FORMED THEREFROM | UNITED STATES DEPARTMENT OF ENERGY | 2012-04-26 | — | — | US | disclosed |
| US-8106393-B2 | Substituted benzazoloporphyrazines for polymerization and surface attachment and articles formed therefrom | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-01-31 | — | — | US | disclosed |
| US-20120004384-A1 | SUBSTITUTED BENZAZOLOPORPHYRAZINES FOR POLYMERIZATION AND SURFACE ATTACHMENT AND ARTICLES FORMED THEREFROM | UNITED STATES DEPARTMENT OF ENERGY | 2012-01-05 | — | — | US | disclosed |
| US-7919770-B2 | Substituted benzazoloporphyrazines for polymerization and surface attachment and articles formed therefrom | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-04-05 | — | — | US | disclosed |
| US-20110015388-A1 | Substituted benzazoloporphyrazines for polymerization and surface attachment and articles formed therefrom | UNITED STATES DEPARTMENT OF ENERGY | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004384-A1 | SUBSTITUTED BENZAZOLOPORPHYRAZINES FOR POLYMERIZATION AND SURFACE ATTACHMENT AND ARTICLES FORMED THEREFROM | PNMT, HNMT, COMT | TLR7 2409/4885KCNH2 762/4885PPARG 2930/4885 |
| US-20120101243-A1 | SUBSTITUTED BENZAZOLOPORPHYRAZINES FOR POLYMERIZATION AND SURFACE ATTACHMENT AND ARTICLES FORMED THEREFROM | PNMT, HNMT, COMT | TLR7 2409/4885KCNH2 762/4885PPARG 2930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.