Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 3/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | GRK2 | P25098 | 3/20 | 0.35 |
| ▸ | GRK5 | P34947 | 3/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL29507041 | 1.00 | DDB1 (0.38) | DDB1CRBNMPOGRK2GRK5 | |
| SCHEMBL26683917 | 0.95 | CRBN (0.41) | DDB1CRBNMPOGRK2GRK5 | |
| SCHEMBL30688300 | 0.84 | DDB1 (0.40) | DDB1CRBNLMNATP53THRB | |
| SCHEMBL26683550 | 0.84 | DDB1 (0.40) | DDB1CRBNLMNATP53THRB | |
| SCHEMBL26683846 | 0.83 | LMNA (0.46) | DDB1CRBNMGLLLMNATP53 | |
| SCHEMBL26842027 | 0.78 | DDB1 (0.44) | DDB1CRBNLMNATHRBGAA | |
| SCHEMBL29507093 | 0.76 | GPR119 (0.50) | DDB1CRBNGPR119 | |
| SCHEMBL25430509 | 0.76 | GPR119 (0.50) | DDB1CRBNGPR119 | |
| SCHEMBL26683931 | 0.73 | MPO (0.41) | DDB1CRBNMPOGRK2GRK5 | |
| Formic Acid SCHEMBL25427830 | 0.72 | APP (0.43) | DDB1CRBNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4221756-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | Astrazeneca AB (SE) | 2023-08-09 | — | — | EP | disclosed |