Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25831704 | 0.95 | DDB1 (0.42) | DDB1CRBNMEN1KMT2AUSP2 | |
| SCHEMBL25250155 | 0.86 | TLR9 (0.43) | DDB1CRBNMEN1KMT2AUSP2 | |
| SCHEMBL25296825 | 0.84 | TLR9 (0.45) | DDB1CRBNMEN1KMT2AUSP2 | |
| SCHEMBL25260977 | 0.81 | PDE4B (0.46) | MEN1KMT2AUSP2HPGDNPSR1 | |
| SCHEMBL30484134 | 0.80 | TLR9 (0.44) | DDB1CRBNMEN1KMT2AUSP2 | |
| SCHEMBL31188115 | 0.79 | DDB1 (0.47) | DDB1CRBNMEN1KMT2AUSP2 | |
| SCHEMBL25831698 | 0.79 | DDB1 (0.47) | DDB1CRBNMEN1KMT2AUSP2 | |
| SCHEMBL31017625 | 0.78 | TLR9 (0.46) | DDB1CRBNMEN1KMT2AUSP2 | |
| SCHEMBL25830816 | 0.78 | TLR9 (0.46) | DDB1CRBNMEN1KMT2AUSP2 | |
| SCHEMBL30484120 | 0.75 | PDE4B (0.47) | PIK3CDHPGDSMAPTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125907-A1 | DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE, LTD. (KY) | 2023-07-06 | — | — | WO | disclosed |