Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.34 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30381641 | 1.00 | ALDH1A1 (0.37) | ALDH1A1USP2LMNAGAASMN1; SMN2 | |
| SCHEMBL25304050 | 0.87 | HTR6 (0.39) | KMT2AMEN1MAPT | |
| SCHEMBL30381434 | 0.87 | HTR6 (0.39) | KMT2AMEN1MAPT | |
| SCHEMBL30381550 | 0.84 | ALDH1A1 (0.39) | ALDH1A1USP2LMNAGAASMN1; SMN2 | |
| SCHEMBL25428681 | 0.84 | ALDH1A1 (0.39) | ALDH1A1USP2LMNAGAASMN1; SMN2 | |
| SCHEMBL25427656 | 0.80 | PTPN11 (0.39) | ALDH1A1USP2LMNAGAASMN1; SMN2 | |
| SCHEMBL30381664 | 0.80 | PTPN11 (0.39) | ALDH1A1USP2LMNAGAASMN1; SMN2 | |
| SCHEMBL25439518 | 0.79 | ALDH1A1 (0.36) | ALDH1A1USP2LMNAGAASMN1; SMN2 | |
| SCHEMBL25299253 | 0.78 | HTR6 (0.41) | BRD4HTTPOLBALDH3A1NOD1 | |
| SCHEMBL30381621 | 0.78 | HTR6 (0.41) | BRD4HTTPOLBALDH3A1NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107723-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |