Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30381550 | 1.00 | ALDH1A1 (0.39) | ALDH1A1USP2LMNAGAASMN1; SMN2 | |
| SCHEMBL25427425 | 0.84 | ALDH1A1 (0.37) | ALDH1A1USP2LMNAGAASMN1; SMN2 | |
| SCHEMBL30381641 | 0.84 | ALDH1A1 (0.37) | ALDH1A1USP2LMNAGAASMN1; SMN2 | |
| SCHEMBL30381748 | 0.80 | HTR6 (0.38) | LMNAGAAPOLBL3MBTL1ACHE | |
| SCHEMBL25426614 | 0.80 | HTR6 (0.38) | LMNAGAAPOLBL3MBTL1ACHE | |
| SCHEMBL25427656 | 0.76 | PTPN11 (0.39) | ALDH1A1USP2LMNAGAASMN1; SMN2 | |
| SCHEMBL30381664 | 0.76 | PTPN11 (0.39) | ALDH1A1USP2LMNAGAASMN1; SMN2 | |
| SCHEMBL25439518 | 0.76 | ALDH1A1 (0.36) | ALDH1A1USP2LMNAGAASMN1; SMN2 | |
| SCHEMBL25424441 | 0.73 | NPSR1 (0.37) | ALDH1A1USP2LMNAGAASMN1; SMN2 | |
| SCHEMBL25304050 | 0.73 | HTR6 (0.39) | KMT2AMEN1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107723-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |