Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 2/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | C1R | P00736 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25429117 | 0.83 | HSD17B10 (0.55) | HSD17B10EPHX2CNR1TP53MAPT | |
| SCHEMBL25432084 | 0.80 | HSD17B10 (0.46) | HSD17B10 | |
| SCHEMBL25954056 | 0.80 | HSD17B10 (0.46) | HSD17B10EPHX2TGFBR1TTBK1 | |
| SCHEMBL30544062 | 0.80 | HSD17B10 (0.46) | HSD17B10EPHX2TGFBR1TTBK1 | |
| SCHEMBL25430635 | 0.73 | HSD17B10 (0.51) | HSD17B10EPHX2 | |
| SCHEMBL5347641 | 0.71 | ABL1 (0.62) | HSD17B10ABL1BCRCYP1A2CYP3A4 | |
| SCHEMBL25379061 | 0.70 | EGFR (0.48) | HSD17B10ABL1BCRCYP1A2CYP3A4 | |
| SCHEMBL25952223 | 0.70 | TEAD1 (0.41) | AURKAAURKBTAS2R14TP53MAPT | |
| SCHEMBL5344234 | 0.69 | ABL1 (0.56) | HSD17B10CNR1ABL1BCRCYP1A2 | |
| SCHEMBL25430373 | 0.68 | EPHX2 (0.44) | EPHX2AURKAAURKBCYP1A2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |