Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 10/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25429117 | 0.83 | HSD17B10 (0.55) | HSD17B10EPHX2TRPV1 | |
| SCHEMBL25429394 | 0.80 | HSD17B10 (0.52) | HSD17B10TRPV1 | |
| SCHEMBL25431622 | 0.80 | HSD17B10 (0.51) | HSD17B10EPHX2TRPV1 | |
| SCHEMBL25954056 | 0.74 | HSD17B10 (0.46) | HSD17B10EPHX2TRPV1 | |
| SCHEMBL30544062 | 0.74 | HSD17B10 (0.46) | HSD17B10EPHX2TRPV1 | |
| SCHEMBL30544072 | 0.74 | TRPV1 (0.46) | EPHX2TRPV1KDR | |
| SCHEMBL25430955 | 0.74 | TRPV1 (0.46) | EPHX2TRPV1KDR | |
| SCHEMBL25427626 | 0.73 | HSD17B10 (0.51) | HSD17B10TRPV1KDR | |
| SCHEMBL25428669 | 0.73 | HSD17B10 (0.47) | HSD17B10EPHX2 | |
| SCHEMBL25974137 | 0.73 | TRPV1 (0.49) | EPHX2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |