Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.40 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30544062 | 1.00 | HSD17B10 (0.46) | HSD17B10EPHX2TTBK1EGFRTRPV1 | |
| SCHEMBL25428669 | 0.80 | HSD17B10 (0.47) | HSD17B10EPHX2TTBK1TGFBR1 | |
| SCHEMBL25430635 | 0.74 | HSD17B10 (0.51) | HSD17B10EPHX2TRPV1 | |
| SCHEMBL25432084 | 0.69 | HSD17B10 (0.46) | HSD17B10 | |
| SCHEMBL22542860 | 0.68 | EPHX2 (0.54) | EPHX2EGFR | |
| SCHEMBL25377441 | 0.67 | EPHX2 (0.47) | EPHX2TRPV1 | |
| SCHEMBL30482543 | 0.67 | EPHX2 (0.47) | EPHX2TRPV1 | |
| SCHEMBL30482575 | 0.66 | KCNQ3 (0.47) | EPHX2TRPV1TRPA1KCNQ3KCNQ2 | |
| SCHEMBL25378382 | 0.66 | KCNQ3 (0.47) | EPHX2TRPV1TRPA1KCNQ3KCNQ2 | |
| SCHEMBL9400251 | 0.66 | HSD17B10 (1.00) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |