SCHEMBL2542879

SCHEMBL2542879

Oc1ccc([Si](c2ccc(O)cc2)(c2ccc(O)cc2)c2ccc(O)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 0.57
NFKB1 P19838 3/20 0.57
HIF1A Q16665 3/20 0.57
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
NPC1 O15118 2/20 0.57
MAPT P10636 2/20 0.57
RAB9A P51151 2/20 0.57
ALDH1A1 P00352 2/20 0.57
CA3 P07451 2/20 0.57
CYP3A4 P08684 2/20 0.57
HSD17B10 Q99714 2/20 0.57
CA14 Q9ULX7 2/20 0.57
KDM4E B2RXH2 2/20 0.57
CA12 O43570 1/20 0.57
GMNN O75496 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
LMNA P02545 1/20 0.57
TYR P14679 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14007757 0.91 ESR1 (0.65) ALOX15NFKB1HIF1AMEN1KMT2A
SCHEMBL2780223 0.88 ESR1 (0.65) ALOX15NFKB1HIF1AMEN1KMT2A
SCHEMBL10314165 0.88 ESR1 (0.65) ALOX15NFKB1HIF1AMEN1KMT2A
SCHEMBL15684574 0.76 ALOX15 (0.53) ALOX15NFKB1HIF1AMEN1KMT2A
Hydroquinone SCHEMBL11511669 0.76 ALOX15 (1.00) ALOX15NFKB1HIF1AMEN1KMT2A
Hydroquinone SCHEMBL460669 0.76 ALOX15 (1.00) ALOX15NFKB1HIF1AMEN1KMT2A
Hydroquinone SCHEMBL15516 0.76
SCHEMBL2144488 0.73 ESR1 (0.56) ALOX15NFKB1HIF1AMEN1KMT2A
SCHEMBL9165768 0.73 MEN1 (0.50) ALOX15NFKB1HIF1AMEN1KMT2A
SCHEMBL834965 0.73 ESR1 (0.80) ALOX15NFKB1HIF1AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8994016-B2 Dielectric layer for an electronic device XEROX CORPORATION (US) 2015-03-31 US claimed
US-20130331512-A1 DIELECTRIC LAYER FOR AN ELECTRONIC DEVICE XEROX CORPORATION (US) 2013-12-12 US claimed
US-20110260114-A1 SEMICONDUCTING COMPOSITION XEROX CORPORATION (US) 2011-10-27 US claimed
US-20100301344-A1 DIELECTRIC LAYER FOR AN ELECTRONIC DEVICE XEROX CORPORATION (US) 2010-12-02 US claimed
EP-2256797-A2 Dielectric layer for an electronic device Xerox Corporation (US) 2010-12-01 EP claimed
US-20080044757-A1 demonstrate a glass transition temperature significantly above room temperature as well as a low tendency towards crystallization; have a tetrahedral silane molecular core with four phenyl groups or four biphenyl groups CORNELL RESEARCH FOUNDATION, INC. (US) 2008-02-21 US claimed
US-10294255-B1 Multifunctional crosslinking agent, crosslinked polymer, and method of making same THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2019-05-21 US disclosed
US-9255186-B2 Thermosetting resins with enhanced cure characteristics containing organofunctional silane moieties THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2016-02-09 US disclosed
US-9217064-B2 Thermosetting resins with enhanced cure characteristics containing organofunctional silane moieties THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2015-12-22 US disclosed
US-20150197606-A1 THERMOSETTING RESINS WITH ENHANCED CURE CHARACTERISTICS CONTAINING ORGANOFUNCTIONAL SILANE MOIETIES GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2015-07-16 US disclosed
US-8994016-B2 Dielectric layer for an electronic device XEROX CORPORATION (US) 2015-03-31 US disclosed
US-20140206812-A1 THERMOSETTING RESINS WITH ENHANCED CURE CHARACTERISTICS CONTAINING ORGANOFUNCTIONAL SILANE MOIETIES GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2014-07-24 US disclosed
US-20130331512-A1 DIELECTRIC LAYER FOR AN ELECTRONIC DEVICE XEROX CORPORATION (US) 2013-12-12 US disclosed
US-20100301344-A1 DIELECTRIC LAYER FOR AN ELECTRONIC DEVICE XEROX CORPORATION (US) 2010-12-02 US disclosed
EP-2256797-A2 Dielectric layer for an electronic device Xerox Corporation (US) 2010-12-01 EP disclosed
US-20100197876-A1 PHOTOCURABLE COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-08-05 US disclosed
US-7452658-B2 Molecular glass photoresists CORNELL UNIVERSITY (US) 2008-11-18 US disclosed
US-7452658-B2 Molecular glass photoresists CORNELL UNIVERSITY (US) 2008-11-18 US disclosed
US-20080044757-A1 demonstrate a glass transition temperature significantly above room temperature as well as a low tendency towards crystallization; have a tetrahedral silane molecular core with four phenyl groups or four biphenyl groups CORNELL RESEARCH FOUNDATION, INC. (US) 2008-02-21 US disclosed
US-20080044757-A1 demonstrate a glass transition temperature significantly above room temperature as well as a low tendency towards crystallization; have a tetrahedral silane molecular core with four phenyl groups or four biphenyl groups CORNELL RESEARCH FOUNDATION, INC. (US) 2008-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10294255-B1 Multifunctional crosslinking agent, crosslinked polymer, and method of making same PARN, PAICS, PAM ALOX15 1652/4885NFKB1 4648/4885HIF1A 1031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.