Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30180938 | 0.84 | TSHR (0.48) | L3MBTL1TSHRLMNAKMT2AGALR3 | |
| SCHEMBL25986461 | 0.84 | TSHR (0.48) | L3MBTL1TSHRLMNAKMT2AGALR3 | |
| SCHEMBL12461610 | 0.84 | TSHR (0.48) | L3MBTL1TSHRLMNAKMT2AGALR3 | |
| SCHEMBL25976534 | 0.82 | TSHR (0.44) | L3MBTL1TSHRLMNAKMT2AALDH1A1 | |
| SCHEMBL30180597 | 0.81 | ALDH1A1 (0.36) | L3MBTL1TSHRLMNAKMT2AALDH1A1 | |
| SCHEMBL24256710 | 0.81 | ALDH1A1 (0.36) | L3MBTL1TSHRLMNAKMT2AALDH1A1 | |
| SCHEMBL25346410 | 0.81 | ALDH1A1 (0.36) | L3MBTL1TSHRLMNAKMT2AALDH1A1 | |
| SCHEMBL26879311 | 0.81 | ALDH1A1 (0.36) | L3MBTL1TSHRLMNAKMT2AALDH1A1 | |
| SCHEMBL19730738 | 0.73 | L3MBTL1 (0.42) | L3MBTL1ELANEALDH1A1MAPT | |
| SCHEMBL12767577 | 0.72 | TSHR (0.40) | L3MBTL1TSHRELANELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250091-A1 | ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES | LYCIA THERAPEUTICS, INC. | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250091-A1 | ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES | ASGR1, LAMP2, FCGR2A | L3MBTL1 2462/4885TSHR 215/4885ELANE 2398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.