Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 6/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | BAD | Q92934 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30544057 | 1.00 | SCN9A (0.44) | SCN9ASCN5ATRPV1SCN8ASCN10A | |
| SCHEMBL25429484 | 0.94 | SCN8A (0.43) | SCN9ASCN5ATRPV1SCN8ASCN10A | |
| SCHEMBL30544026 | 0.91 | TRPV1 (0.39) | SCN9ASCN5ATRPV1SCN8ASCN10A | |
| SCHEMBL25428113 | 0.91 | TRPV1 (0.39) | SCN9ASCN5ATRPV1SCN8ASCN10A | |
| SCHEMBL25429273 | 0.88 | NOD2 (0.37) | SCN9ASCN5ATRPV1SCN8ASCN10A | |
| SCHEMBL25429756 | 0.87 | ICMT (0.39) | SCN9ASCN5ATRPV1SCN8ASCN10A | |
| SCHEMBL30544045 | 0.87 | ICMT (0.39) | SCN9ASCN5ATRPV1SCN8ASCN10A | |
| SCHEMBL30544047 | 0.86 | SCN9A (0.42) | SCN9ASCN5A | |
| SCHEMBL25428450 | 0.86 | SCN9A (0.42) | SCN9ASCN5A | |
| SCHEMBL30544106 | 0.84 | PDPK1 (0.40) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |