Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTBK1 | Q5TCY1 | 3/20 | 0.42 |
| ▸ | TTBK2 | Q6IQ55 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 5/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 7/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 7/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25430011 | 0.85 | TTBK1 (0.41) | TTBK1TTBK2HSD17B10ADORA2AADORA1 | |
| SCHEMBL25430475 | 0.79 | HSD17B10 (0.40) | HSD17B10ADORA2AADORA1CYP1A2CYP3A4 | |
| SCHEMBL25431696 | 0.77 | GRM2 (0.38) | BRD4SCN9A | |
| SCHEMBL25429720 | 0.77 | HSD17B10 (0.55) | HSD17B10BRD4SCN8ASCN10ASCN9A | |
| SCHEMBL25432124 | 0.72 | ELANE (0.40) | ADORA2AADORA1 | |
| SCHEMBL25427626 | 0.67 | HSD17B10 (0.51) | TTBK1HSD17B10SCN8ASCN10ABRAF | |
| SCHEMBL2881510 | 0.66 | SCN8A (0.43) | SCN8ASCN10A | |
| SCHEMBL28638978 | 0.66 | L3MBTL1 (0.52) | MAPK14 | |
| SCHEMBL21145512 | 0.66 | ADORA2A (0.57) | HSD17B10ADORA2AADORA1TGFBR1 | |
| SCHEMBL28672016 | 0.66 | NCOA1 (0.62) | BRD4MAPK14SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |