Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | C1R | P00736 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25432084 | 0.80 | HSD17B10 (0.46) | HSD17B10SLC6A2SLC6A4SLC6A3DHFR | |
| SCHEMBL25430366 | 0.79 | TTBK1 (0.42) | HSD17B10ADORA2AADORA1CYP1A2CYP3A4 | |
| SCHEMBL25430647 | 0.78 | HSD17B10 (0.55) | HSD17B10SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL25952233 | 0.76 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3DHFRHTR1A | |
| SCHEMBL25430011 | 0.75 | TTBK1 (0.41) | HSD17B10ADORA2AADORA1TRPV1 | |
| SCHEMBL21145512 | 0.66 | ADORA2A (0.57) | HSD17B10ADORA2AADORA1TGFBR1KDM4E | |
| SCHEMBL25431622 | 0.66 | HSD17B10 (0.51) | HSD17B10GRM5TGFBR1TRPV1 | |
| SCHEMBL25429043 | 0.65 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3HTR1AHTR3A | |
| SCHEMBL25955728 | 0.63 | SLC6A4 (0.54) | SLC6A2SLC6A4SLC6A3DHFRHTR1A | |
| SCHEMBL25978187 | 0.62 | SLC6A2 (0.50) | HSD17B10SLC6A2SLC6A4SLC6A3DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |