Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25431622 | 0.83 | HSD17B10 (0.51) | HSD17B10TRPV1ALDH1A1DYRK1AEPHX2 | |
| SCHEMBL25432084 | 0.82 | HSD17B10 (0.46) | HSD17B10RHEBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25952224 | 0.80 | HSD17B10 (0.39) | HSD17B10TRPV1ALDH1A1MAPTKDM4E | |
| SCHEMBL25429720 | 0.78 | HSD17B10 (0.55) | HSD17B10TRPV1RHEBALDH1A1EPHX2 | |
| SCHEMBL25429117 | 0.78 | HSD17B10 (0.55) | HSD17B10TRPV1ALDH1A1EPHX2MAPT | |
| SCHEMBL25430475 | 0.78 | HSD17B10 (0.40) | HSD17B10TRPV1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25429043 | 0.76 | SLC6A2 (0.38) | TRPV1ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25430317 | 0.76 | HSD17B10 (0.53) | HSD17B10TRPV1ALDH1A1DYRK1AEPHX2 | |
| SCHEMBL9400251 | 0.73 | HSD17B10 (1.00) | HSD17B10ALDH1A1CYP1A2MAPTKDM4E | |
| SCHEMBL25429394 | 0.73 | HSD17B10 (0.52) | HSD17B10TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |