Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.31 |
| ▸ | MAPK6 | Q16659 | 2/20 | 0.31 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.31 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25431622 | 0.85 | HSD17B10 (0.51) | HSD17B10TRPV1ALDH1A1DYRK1AMAPT | |
| SCHEMBL25430344 | 0.85 | TRPV1 (0.41) | HSD17B10TRPV1DYRK1ATRPA1MAPT | |
| SCHEMBL25429893 | 0.80 | HSD17B10 (0.54) | HSD17B10TRPV1ALDH1A1TRPA1 | |
| SCHEMBL25429595 | 0.77 | TRPV1 (0.37) | TRPV1EPHX2KIF11MAPK1 | |
| SCHEMBL25430647 | 0.76 | HSD17B10 (0.55) | HSD17B10TRPV1ALDH1A1DYRK1AMAPT | |
| SCHEMBL25427626 | 0.75 | HSD17B10 (0.51) | HSD17B10TRPV1ALDH1A1TRPA1KIF11 | |
| SCHEMBL25954052 | 0.73 | TRPV1 (0.37) | TRPV1EPHX2GSK3BKIF11 | |
| SCHEMBL30544122 | 0.73 | TRPV1 (0.37) | TRPV1EPHX2GSK3BKIF11 | |
| SCHEMBL25974048 | 0.73 | TRPV1 (0.37) | TRPV1ALDH1A1MAPTCCNB2CDK1 | |
| SCHEMBL25428430 | 0.73 | TRPV1 (0.36) | TRPV1TRPA1CCNB2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |