Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 7/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25432160 | 0.81 | PDE4B (0.46) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL31208014 | 0.81 | PDE4B (0.46) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL25431228 | 0.76 | PDK4 (0.37) | DDB1CRBNGPR119 | |
| SCHEMBL30496025 | 0.74 | TRPV3 (0.50) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL31208026 | 0.74 | TRPV3 (0.52) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL26025833 | 0.74 | TRPV3 (0.52) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL25361679 | 0.74 | TRPV3 (0.50) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL25366217 | 0.74 | TRPV3 (0.52) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL25361414 | 0.74 | TRPV3 (0.50) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL25430422 | 0.73 | PDE4B (0.46) | KDM4EALDH1A1HPGDNPSR1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4674841-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2026-01-07 | — | — | EP | disclosed |
| CN-118973578-A | Pharmaceutical compounds | 杜克街生物有限公司 | 2024-11-15 | — | — | CN | disclosed |
| EP-4444305-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |