Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2A | P48426 | 5/20 | 0.59 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GCGR | P47871 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31083321 | 0.84 | SLC22A12 (0.51) | PDE10ALMNACYP1A2CYP3A4PDE5A | |
| SCHEMBL1132618 | 0.83 | PIP4K2A (0.48) | PIP4K2APDE10ANPSR1GRIN1GRIN2B | |
| SCHEMBL7316953 | 0.80 | PIP4K2A (0.48) | PIP4K2APDE10ANPSR1LMNACYP1A2 | |
| SCHEMBL249967 | 0.77 | CA12 (0.49) | PIP4K2APDE10ALMNACYP1A2CYP3A4 | |
| SCHEMBL198911 | 0.74 | ALDH1A1 (0.60) | TTRNPSR1CYP1A2PDE5AL3MBTL1 | |
| SCHEMBL10505170 | 0.74 | PIP4K2A (0.44) | PIP4K2ANPSR1GRIN1GRIN2BPDE3A | |
| SCHEMBL11625024 | 0.73 | PDE5A (0.56) | PDE10AGRIN1GRIN2BPDE5A | |
| SCHEMBL5451 | 0.72 | SMN1; SMN2 (0.51) | NPSR1LMNAGAAL3MBTL1 | |
| SCHEMBL30283197 | 0.72 | SMN1; SMN2 (0.51) | NPSR1LMNAGAAL3MBTL1 | |
| SCHEMBL19955394 | 0.72 | CYP11B1 (0.49) | PDE10ACYP1A2CYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023142641-A1 | PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 成都苑东生物制药股份有限公司 | 2023-08-03 | — | — | WO | disclosed |