⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24665879 | 0.78 | ACHE (0.36) | — | |
| SCHEMBL24666097 | 0.78 | CYP11B1 (0.33) | — | |
| SCHEMBL21070404 | 0.75 | NPC1 (0.46) | — | |
| SCHEMBL9003126 | 0.70 | — | — | |
| SCHEMBL22843159 | 0.65 | MAPT (0.33) | — | |
| SCHEMBL24391449 | 0.65 | DYRK1A (0.38) | — | |
| SCHEMBL31710819 | 0.64 | — | — | |
| SCHEMBL25440556 | 0.64 | — | — | |
| SCHEMBL23194292 | 0.63 | CACNA1G (0.30) | — | |
| SCHEMBL25364854 | 0.63 | FAAH (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234017-A2 | 4-METHYLSULFONYL-SUBSTITUTED PIPERIDINE UREA COMPOUNDS USEFUL FOR THE TREATMENT OF CARDIAC DISORDERS SUCH AS DILATED CARDIOMYOPATHY (DCM) | MyoKardia, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |