SCHEMBL2543497

SCHEMBL2543497

CCC[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(N)=O

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 7/20 0.59
▸ NPY1R P25929 3/20 0.59
▸ NPY2R P49146 3/20 0.59
▸ NPY4R P50391 3/20 0.59
▸ PRKACB P22694 1/20 0.57
▸ UTS2R Q9UKP6 1/20 0.53
▸ NPBWR1 P48145 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29511721 0.95 GHSR (0.55) GHSRNPY1RNPY2RNPY4RPRKACB
SCHEMBL29641082 0.94 GHSR (0.61) GHSRNPY1RNPY2RNPY4RPRKACB
SCHEMBL29641066 0.94 GHSR (0.61) GHSRNPY1RNPY2RNPY4RPRKACB
SCHEMBL29483769 0.94 GHSR (0.60) GHSRPRKACBUTS2RNPBWR1
SCHEMBL29641173 0.94 GHSR (0.60) GHSRPRKACBUTS2RNPBWR1
SCHEMBL29483770 0.94 GHSR (0.60) GHSRPRKACBUTS2RNPBWR1
SCHEMBL29641180 0.94 GHSR (0.58) GHSRNPY1RNPY2RNPY4RPRKACB
SCHEMBL30118086 0.93 GHSR (0.57) GHSRNPY1RNPY2RNPY4RPRKACB
SCHEMBL30773914 0.93 GHSR (0.57) GHSRNPY1RNPY2RNPY4RPRKACB
SCHEMBL31193750 0.91 NPY4R (0.58) GHSRNPY1RNPY2RNPY4RPRKACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110263975-A1 FLUORESCENT PROBES HAVING A POLYMERIC BACKBONE GE HEALTHCARE AS (NO) 2011-10-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110263975-A1 FLUORESCENT PROBES HAVING A POLYMERIC BACKBONE CD38, ARFGAP1, ADCYAP1R1 GHSR 3866/4885NPY1R 1692/4885NPY2R 2352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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