SCHEMBL29483770

SCHEMBL29483770

N=C(N)NCCC[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(N)=O

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 6/20 0.60
▸ PRKACB P22694 1/20 0.58
▸ UTS2R Q9UKP6 1/20 0.56
▸ NPBWR1 P48145 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29641173 1.00 GHSR (0.60) GHSRPRKACBUTS2RNPBWR1
SCHEMBL29483769 1.00 GHSR (0.60) GHSRPRKACBUTS2RNPBWR1
SCHEMBL29641066 0.96 GHSR (0.61) GHSRPRKACBUTS2R
SCHEMBL29641082 0.96 GHSR (0.61) GHSRPRKACBUTS2R
SCHEMBL29641180 0.95 GHSR (0.58) GHSRPRKACBUTS2RNPBWR1
SCHEMBL29483773 0.94 GHSR (0.56) GHSRPRKACBUTS2RNPBWR1
SCHEMBL29483771 0.94 GHSR (0.56) GHSRPRKACBUTS2RNPBWR1
SCHEMBL30773914 0.94 GHSR (0.57) GHSRPRKACBUTS2RNPBWR1
SCHEMBL30118086 0.94 GHSR (0.57) GHSRPRKACBUTS2RNPBWR1
SCHEMBL29389812 0.94 NPY1R (0.56) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12558346-B2 Methods and compositions for delivery of biotin to mitochondria SOCIAL PROFIT NETWORK (US) 2026-02-24 — — US claimed
US-20250064786-A1 Methods and Compositions for Delivery of Biotin to Mitochondria SOCIAL PROFIT NETWORK (US) 2025-02-27 — — US claimed
CN-116390723-B Methods and compositions for delivery of biotin to mitochondria 社会利益网络公司 2024-12-31 — — CN claimed
US-20240108740-A1 THERAPEUTIC COMPOSITIONS INCLUDING SPN10 AND USES THEREOF STEALTH BIOTHERAPEUTICS INC. (US) 2024-04-04 — — US claimed
EP-4210695-A1 METHODS AND COMPOSITIONS FOR DELIVERY OF BIOTIN TO MITOCHONDRIA Social Profit Network (US) 2023-07-19 — — EP claimed
US-11389431-B2 Methods and compositions for delivery of biotin to mitochondria SOCIAL PROFIT NETWORK (US) 2022-07-19 — — US claimed
WO-2022055811-A1 METHODS AND COMPOSITIONS FOR DELIVERY OF BIOTIN TO MITOCHONDRIA SOCIAL PROFIT NETWORK (US) 2022-03-17 — — WO claimed
US-20220071964-A1 Methods and Compositions for Delivery of Biotin to Mitochondria SOCIAL PROFIT NETWORK (US) 2022-03-10 — — US claimed
US-12558346-B2 Methods and compositions for delivery of biotin to mitochondria SOCIAL PROFIT NETWORK (US) 2026-02-24 — — US disclosed
US-20250064786-A1 Methods and Compositions for Delivery of Biotin to Mitochondria SOCIAL PROFIT NETWORK (US) 2025-02-27 — — US disclosed
CN-116390723-B Methods and compositions for delivery of biotin to mitochondria 社会利益网络公司 2024-12-31 — — CN disclosed
US-12150932-B2 Methods and compositions for delivery of biotin to mitochondria SOCIAL PROFIT NETWORK (US) 2024-11-26 — — US disclosed
US-20240108740-A1 THERAPEUTIC COMPOSITIONS INCLUDING SPN10 AND USES THEREOF STEALTH BIOTHERAPEUTICS INC. (US) 2024-04-04 — — US disclosed
US-20240108740-A1 THERAPEUTIC COMPOSITIONS INCLUDING SPN10 AND USES THEREOF STEALTH BIOTHERAPEUTICS INC. (US) 2024-04-04 — — US disclosed
US-11602523-B2 Methods and compositions for delivery of biotin to mitochondria SOCIAL PROFIT NETWORK (US) 2023-03-14 — — US disclosed
US-20230043530-A1 Methods and Compositions for Delivery of Biotin to Mitochondria SOCIAL PROFIT NETWORK (US) 2023-02-09 — — US disclosed
US-20220347160-A1 Methods and Compositions for Delivery of Biotin to Mitochondria SOCIAL PROFIT NETWORK (US) 2022-11-03 — — US disclosed
US-11389431-B2 Methods and compositions for delivery of biotin to mitochondria SOCIAL PROFIT NETWORK (US) 2022-07-19 — — US disclosed
WO-2022055811-A1 METHODS AND COMPOSITIONS FOR DELIVERY OF BIOTIN TO MITOCHONDRIA SOCIAL PROFIT NETWORK (US) 2022-03-17 — — WO disclosed
US-20220071964-A1 Methods and Compositions for Delivery of Biotin to Mitochondria SOCIAL PROFIT NETWORK (US) 2022-03-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12558346-B2 Methods and compositions for delivery of biotin to mitochondria PDF, MARS2, NLN GHSR 4206/4885PRKACB 4742/4885UTS2R 4162/4885
US-20240108740-A1 THERAPEUTIC COMPOSITIONS INCLUDING SPN10 AND USES THEREOF S100A10, SPG11, TMSB10 GHSR 2407/4885PRKACB 2951/4885UTS2R 699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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