Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30584837 | 1.00 | LMNA (0.62) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL30584862 | 0.91 | TSHR (0.59) | LMNAMEN1KMT2AMAPTTP53 | |
| SCHEMBL30584890 | 0.90 | LMNA (0.65) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL31546349 | 0.89 | ALDH1A1 (0.54) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL31546346 | 0.89 | LMNA (0.66) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL30584903 | 0.89 | ALDH1A1 (0.56) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL31546388 | 0.89 | HTT (0.60) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL25434291 | 0.89 | HTT (0.60) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL25437574 | 0.88 | MEN1 (0.56) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL30584916 | 0.88 | MEN1 (0.56) | LMNAMEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023177700-A2 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2023-09-21 | — | — | WO | disclosed |