⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7627037 | 0.81 | TSHR (0.44) | — | |
| SCHEMBL27480761 | 0.77 | — | — | |
| SCHEMBL237795 | 0.75 | TSHR (0.50) | — | |
| SCHEMBL515199 | 0.75 | TSHR (0.43) | — | |
| SCHEMBL2789194 | 0.75 | ALDH1A1 (0.50) | — | |
| SCHEMBL25435249 | 0.75 | — | — | |
| SCHEMBL1422175 | 0.73 | — | — | |
| SCHEMBL6501758 | 0.73 | — | — | |
| SCHEMBL7945150 | 0.73 | DGKA (0.42) | — | |
| SCHEMBL2762078 | 0.73 | DGKA (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2391602-A1 | CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2011-12-07 | — | — | EP | disclosed |
| WO-2010080481-A1 | CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-07-15 | — | — | WO | disclosed |
| EP-1425262-A4 | ACYLTHIOLS AND COMPONENT THIOL COMPOSITIONS AS ANTI-HIV AND ANTI-RETROVIRAL AGENTS | US GOV HEALTH & HUMAN SERV (US) | 2006-03-08 | — | — | EP | disclosed |
| EP-1425262-A1 | ACYLTHIOLS AND COMPONENT THIOL COMPOSITIONS AS ANTI-HIV AND ANTI-RETROVIRAL AGENTS | The Gov. of USA, as represented by the Secretary, Dept. of Health and Human services, National Institutes of Health (US) | 2004-06-09 | — | — | EP | disclosed |
| WO-2003014062-A1 | ACYLTHIOLS AND COMPONENT THIOL COMPOSITIONS AS ANTI-HIV AND ANTI-RETROVIRAL AGENTS | THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2003-02-20 | — | — | WO | disclosed |