Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4648177 | 1.00 | CTSL (0.47) | CTSLCTSBCAPN1NAAA | |
| SCHEMBL30140807 | 0.88 | CTSL (0.45) | CTSLCTSBCAPN1 | |
| SCHEMBL31644645 | 0.88 | CTSL (0.45) | CTSLCTSBCAPN1 | |
| SCHEMBL30140779 | 0.84 | CTSL (0.45) | CTSLCTSBCAPN1 | |
| SCHEMBL30140819 | 0.82 | CTSL (0.43) | CTSLCTSBCAPN1NAAA | |
| SCHEMBL30396500 | 0.82 | CTSL (0.42) | CTSLCTSBCAPN1NAAA | |
| SCHEMBL24029103 | 0.81 | CTSL (0.42) | CTSLCTSB | |
| SCHEMBL14838051 | 0.81 | NFKB1 (0.43) | — | |
| SCHEMBL23782042 | 0.81 | NFKB1 (0.43) | — | |
| SCHEMBL4954867 | 0.81 | NFKB1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150790-A2 | NOVEL AND HIGHLY SELECTIVE SARS-COV-2 MPRO INHIBITORS | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2023-08-10 | — | — | WO | disclosed |