Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31644645 | 0.89 | CTSL (0.45) | CTSLCTSBCAPN1 | |
| SCHEMBL25435650 | 0.88 | CTSL (0.47) | CTSLCTSBCAPN1 | |
| SCHEMBL4648177 | 0.88 | CTSL (0.47) | CTSLCTSBCAPN1 | |
| SCHEMBL30140819 | 0.84 | CTSL (0.43) | CTSLCTSBCAPN1CTSK | |
| SCHEMBL30140779 | 0.81 | CTSL (0.45) | CTSLCTSBCAPN1 | |
| SCHEMBL8278581 | 0.81 | — | — | |
| SCHEMBL8276856 | 0.81 | — | — | |
| SCHEMBL30396500 | 0.79 | CTSL (0.42) | CTSLCTSBCAPN1 | |
| SCHEMBL30494483 | 0.79 | CAPN1 (0.37) | CTSLCAPN1 | |
| SCHEMBL24754878 | 0.75 | CTSS (0.39) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266363-A1 | PROTEASE INHIBITORS FOR THE TREATMENT OF CORONAVIRUS INFECTIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-12-22 | — | — | WO | disclosed |