SCHEMBL2543584

SCHEMBL2543584

Cc1cn([C@@]2(c3ccc([N+](=O)[O-])cc3)C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.39
TK1 P04183 5/20 0.37
ALDH1A1 P00352 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL548541 0.96 TYMS (0.42) TYMSTK1
SCHEMBL28475424 0.87 TYMS (0.45) TYMSTK1
SCHEMBL548543 0.87 TYMS (0.52) TYMSTK1
SCHEMBL6854761 0.87 TYMS (0.41) TYMSTK1
SCHEMBL27508379 0.86 TK1 (0.39) TK1
SCHEMBL9947616 0.84 TYMS (0.38) TYMSTK1
SCHEMBL7040496 0.83 TYMS (0.37) TYMSTK1
SCHEMBL135210 0.78 TK1 (0.44) TK1ALDH1A1NPSR1
SCHEMBL16187026 0.78 TK1 (0.44) TK1ALDH1A1NPSR1
SCHEMBL29364921 0.77 TK1 (0.45) TK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3206723-A1 BIOLOGICAL INDICATOR American Sterilizer Company (US) 2017-08-23 EP claimed
US-9701968-B2 Biological indicator AMERICAN STERILIZER COMPANY (US) 2017-07-11 US claimed
US-20160312263-A1 BIOLOGICAL INDICATOR AMERICAN STERILIZER CO (US) 2016-10-27 US claimed
WO-2016060714-A1 BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY (US) 2016-04-21 WO claimed
US-20160102335-A1 BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY 2016-04-14 US claimed
US-8507248-B2 Genetically engineered biological indicator AMERICAN STERILIZER COMPANY (US) 2013-08-13 US claimed
US-8173389-B2 Process for determining the effectiveness of a sterilization AMERICAN STERILIZER COMPANY (US) 2012-05-08 US claimed
US-20090117603-A1 STERILIZATION INDICATOR FRANCISKOVICH PHILLIP P 2009-05-07 US claimed
US-20080070231-A1 Reporter genes taken up by microorganism, and repressor gene inhibits expression AMERICAN STERILIZER COMPANY 2008-03-20 US claimed
US-20080070272-A1 STERILIZATION INDICATOR AMERICAN STERILIZER COMPANY 2008-03-20 US claimed
US-12298207-B2 Calibration slides for digital pathology VENTANA MEDICAL SYSTEMS, INC. (US) 2025-05-13 US disclosed
WO-2024229043-A2 ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 (ENPP1)-BINDING VARIABLE HEAVY (VH) DOMAINS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-11-07 WO disclosed
US-20240175789-A1 CALIBRATION SLIDES FOR DIGITAL PATHOLOGY VENTANA MED SYST INC (US) 2024-05-30 US disclosed
US-11946838-B2 Calibration slides for digital pathology VENTANA MEDICAL SYSTEMS, INC. (US) 2024-04-02 US disclosed
WO-2023076866-A1 TRICYCLIC SULFOXIMINE INHIBITORS OF ENPP1 VOLASTRA THERAPEUTICS, INC. (US) 2023-05-04 WO disclosed
US-6623955-B2 Exposing source of active enzyme to sterilization cycle, contacting enzyme after cycle with aqueous buffer and substrate specific for and reactive with active enzyme to form enzyme modified product, detecting viable microorganisms 3M INNOVATIVE PROPERTIES COMPANY 2003-09-23 US disclosed
US-20030157588-A1 Exposing source of active enzyme to sterilization cycle, contacting enzyme after cycle with aqueous buffer and substrate specific for and reactive with active enzyme to form enzyme modified product, detecting viable microorganisms 3M INNOVATIVE PROPERTIES COMPANY 2003-08-21 US disclosed
WO-2003040340-A2 NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 161P2F10B USEFUL IN TREATMENT AND DETECTION OF CANCER AGENSYS, INC. (US) 2003-05-15 WO disclosed
US-20030077688-A1 Rapid read-out biological indicator MINNESOTA MINING AND MANUFACTURING COMPANY TO 3M INNOVATIVE PROPERTIES COMPANY 2003-04-24 US disclosed
EP-0371682-A2 Rapid method for determining efficacy of a sterilization cycle and rapid read-out biological indicator MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-06-06 EP disclosed