Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 3/20 | 0.52 |
| ▸ | TK1 | P04183 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28475424 | 0.94 | TYMS (0.45) | TYMSTK1POLB | |
| Phosphoric Acid SCHEMBL548541 | 0.89 | TYMS (0.42) | TYMSTK1 | |
| SCHEMBL2543584 | 0.87 | TYMS (0.39) | TYMSTK1 | |
| SCHEMBL6854761 | 0.85 | TYMS (0.41) | TYMSTK1 | |
| SCHEMBL7243147 | 0.81 | TK1 (0.51) | TYMSTK1POLB | |
| SCHEMBL26125047 | 0.77 | TK1 (0.48) | TYMSTK1POLB | |
| Thymidine Monophosphate SCHEMBL20797966 | 0.75 | TYMS (0.75) | TYMSTK1POLB | |
| SCHEMBL17515060 | 0.74 | TK1 (0.51) | TYMSTK1POLB | |
| SCHEMBL6386150 | 0.73 | TK1 (0.42) | TYMSTK1 | |
| SCHEMBL27508379 | 0.73 | TK1 (0.39) | TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267044-A1 | GENETICALLY ENGINEERED BIOLOGICAL INDICATOR | FRANCISKOVICH PHILLIP P | 2010-10-21 | — | — | US | claimed |
| EP-2084294-A2 | STERILIZATION INDICATOR | American Sterilizer Company (US) | 2009-08-05 | — | — | EP | claimed |
| EP-2084293-A2 | GENETICALLY ENGINEERED BIOLOGICAL INDICATOR | American Sterilizer Company (US) | 2009-08-05 | — | — | EP | claimed |
| WO-2008082728-A2 | STERILIZATION INDICATOR | AMERICAN STERILIZER COMPANY (US) | 2008-07-10 | — | — | WO | claimed |
| WO-2008079469-A2 | GENETICALLY ENGINEERED BIOLOGICAL INDICATOR | AMERICAN STERILIZER COMPANY (US) | 2008-07-03 | — | — | WO | claimed |
| WO-2026102337-A1 | ENPP1 FOR USE IN THE TREATMENT OF CALCIPHYLAXIS | BIOMARIN PHARMACEUTICAL INC. (US) | 2026-05-15 | — | — | WO | disclosed |
| US-20260049294-A1 | ENPP1 Polypeptides and Methods of Using Same | UNIV YALE (US) | 2026-02-19 | — | — | US | disclosed |
| US-20260041742-A1 | METHOD AND COMPOSITIONS FOR TREATMENT, AMELIORATION, AND/OR PREVENTION OF DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS (DISH) | UNIV YALE (US) | 2026-02-12 | — | — | US | disclosed |
| EP-4688153-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) INHIBITORS FOR THE TREATMENT OF HYPOPHOSPHATASIA | 1Cbio, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| US-20250388882-A1 | COMPOSITIONS FOR TREATING ECTOPIC CALCIFICATION DISORDERS, AND METHODS USING SAME | UNIV YALE (US) | 2025-12-25 | — | — | US | disclosed |
| US-20250367173-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | LIGACHEM BIOSCIENCES INC (KR) | 2025-12-04 | — | — | US | disclosed |
| US-20250368654-A1 | HETEROCYCLIC INHIBITORS OF ENPP1 | VOLASTRA THERAPEUTICS, INC. (US) | 2025-12-04 | — | — | US | disclosed |
| US-5731167-A | DNA SEGMENT CODING FOR A POLYPEPTIDE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-03-24 | — | — | US | disclosed |
| EP-0371682-B1 | Rapid method for determining efficacy of a sterilization cycle and rapid read-out biological indicator | MINNESOTA MINING & MFG (US) | 1996-05-22 | — | — | EP | disclosed |
| WO-1995032221-A9 | AUTOTAXIN: MOTILITY STIMULATING PROTEIN USEFUL IN CANCER DIAGNOSIS AND THERAPY | — | 1996-01-04 | — | — | WO | disclosed |
| WO-1995032221-A2 | AUTOTAXIN: MOTILITY STIMULATING PROTEIN USEFUL IN CANCER DIAGNOSIS AND THERAPY | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1995-11-30 | — | — | WO | disclosed |
| US-5418167-A | Sterilization indicator | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-05-23 | — | — | US | disclosed |
| US-5252484-A | Determination of efficiency of sterilization cycle | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| US-5223401-A | Colorimetric analysis; substrate system producing detectable enzyme-modified product | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-06-29 | — | — | US | disclosed |
| US-5073488-A | Using active enzyme | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250367173-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | ENPP1, ENPP3, SMPD1 | TYMS 276/4885TK1 218/4885POLB 830/4885 |
| US-20250388882-A1 | COMPOSITIONS FOR TREATING ECTOPIC CALCIFICATION DISORDERS, AND METHODS USING SAME | ALPI, ENPP3, ALPP | TYMS 3104/4885TK1 2728/4885POLB 3691/4885 |
| US-20260049294-A1 | ENPP1 Polypeptides and Methods of Using Same | ENPP1, ENPP3, PNP | TYMS 713/4885TK1 463/4885POLB 945/4885 |
| US-20250368654-A1 | HETEROCYCLIC INHIBITORS OF ENPP1 | ENPP1, ENPP3, ENPP2 | TYMS 253/4885TK1 155/4885POLB 1562/4885 |
| US-20260041742-A1 | METHOD AND COMPOSITIONS FOR TREATMENT, AMELIORATION, AND/OR PREVENTION OF DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS (DISH) | SOST, ALB, ENPP2 | TYMS 4190/4885TK1 2638/4885POLB 4258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.