Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20558229 | 0.79 | RIPK1 (0.56) | RIPK1NR1H2NR1H3KCNH2 | |
| SCHEMBL20178113 | 0.72 | RIPK1 (0.59) | RIPK1NR1H2NR1H3 | |
| SCHEMBL27262020 | 0.70 | ALDH1A1 (0.72) | ALDH1A1KDM4EKMT2AL3MBTL1FAAH | |
| SCHEMBL1142467 | 0.70 | ALDH1A1 (0.72) | ALDH1A1KDM4EKMT2AL3MBTL1FAAH | |
| SCHEMBL26775029 | 0.70 | ALDH1A1 (0.72) | ALDH1A1KDM4EKMT2AL3MBTL1FAAH | |
| SCHEMBL12083567 | 0.70 | ALDH1A1 (0.72) | ALDH1A1KDM4EKMT2AL3MBTL1FAAH | |
| SCHEMBL2362569 | 0.70 | ALDH1A1 (0.72) | ALDH1A1KDM4EKMT2AL3MBTL1FAAH | |
| SCHEMBL1142463 | 0.70 | ALDH1A1 (0.72) | ALDH1A1KDM4EKMT2AL3MBTL1FAAH | |
| SCHEMBL22721972 | 0.70 | TMEM97 (0.56) | RIPK1L3MBTL1CHRM2CHRM4CHRM5 | |
| SCHEMBL29540420 | 0.70 | TMEM97 (0.56) | RIPK1L3MBTL1CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4208456-A1 | HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2023-07-12 | — | — | EP | disclosed |