Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5345793 | 0.90 | SMYD3 (0.38) | CHRM1SMYD3CHRM2CHRM3DPP4 | |
| SCHEMBL15864996 | 0.86 | SMYD3 (0.30) | SMYD3 | |
| SCHEMBL23649353 | 0.86 | AKR1C3 (0.34) | CHRM1SMYD3CHRM2CHRM3 | |
| SCHEMBL482006 | 0.84 | NCF1 (0.36) | CHRM1SMYD3CHRM2CHRM3DPP4 | |
| SCHEMBL21998268 | 0.83 | SMYD3 (0.35) | SMYD3 | |
| SCHEMBL619575 | 0.82 | TYMP (0.33) | SMYD3DPP4 | |
| SCHEMBL21997631 | 0.82 | SIGMAR1 (0.36) | SMYD3SIGMAR1 | |
| SCHEMBL7257968 | 0.82 | ITGB3 (0.48) | — | |
| SCHEMBL29055045 | 0.82 | SMYD3 (0.35) | CHRM1SMYD3CHRM2CHRM3DPP4 | |
| SCHEMBL3504553 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4194457-A1 | COMPOUND FOR TARGETING AND DEGRADING PROTEIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Leadingtac Pharmaceutical Co., Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |