Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 13/20 | 1.00 |
| ▸ | F11 | P03951 | 9/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29407533 | 0.95 | KLKB1 (1.00) | KLKB1F11 | |
| SCHEMBL29407550 | 0.91 | KLKB1 (0.83) | KLKB1F11 | |
| SCHEMBL29405129 | 0.91 | KLKB1 (0.83) | KLKB1F11 | |
| SCHEMBL22981556 | 0.91 | KLKB1 (0.83) | KLKB1F11 | |
| SCHEMBL29407471 | 0.88 | F11 (1.00) | KLKB1F11 | |
| SCHEMBL22981918 | 0.88 | KLKB1 (0.81) | KLKB1F11 | |
| SCHEMBL29697531 | 0.88 | KLKB1 (0.81) | KLKB1F11 | |
| SCHEMBL22993179 | 0.88 | F11 (0.84) | KLKB1F11 | |
| SCHEMBL22981929 | 0.87 | KLKB1 (1.00) | KLKB1F11 | |
| SCHEMBL29407077 | 0.87 | KLKB1 (1.00) | KLKB1F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250080-A1 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LTD (GB) | 2023-08-10 | — | — | US | disclosed |
| CN-114206852-A | Plasma kallikrein inhibitors | 卡尔维斯塔制药有限公司 | 2022-03-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250080-A1 | ENZYME INHIBITORS | SERPINB1, KLKB1, SERPINE1 | KLKB1 2/4885F11 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.