Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14616506 | 0.88 | PTGDR2 (0.38) | PTGDR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL12479163 | 0.88 | CA12 (0.47) | PTGDR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL14089367 | 0.84 | KDM4E (0.45) | ALDH1A1KDM4EMEN1KMT2ASLC1A3 | |
| SCHEMBL14089363 | 0.81 | KMT2A (0.36) | PTGDR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL14089360 | 0.77 | PTGDR2 (0.38) | PTGDR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7674203 | 0.76 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL812155 | 0.76 | SHMT1 (0.39) | PTGDR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL12245351 | 0.74 | USP7 (0.37) | PTGDR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7102760 | 0.73 | SUCNR1 (0.43) | PTGDR2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL861566 | 0.72 | PTGS1 (0.51) | PTGDR2ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859466-B2 | Oxaspirocyclic spiro-substituted tetramic acid and tetronic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2014-10-14 | — | — | US | disclosed |
| US-20110263424-A1 | Oxaspirocyclic Spiro-Substituted Tetramic Acid and Tetronic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263424-A1 | Oxaspirocyclic Spiro-Substituted Tetramic Acid and Tetronic Acid Derivatives | TBCA, POF1B, DDT | PTGDR2 2181/4885ALDH1A1 1939/4885KDM4E 3681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.