Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.53 |
| ▸ | MAOB | P27338 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | UNG | P13051 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1279762 | 0.85 | MAOA (0.55) | MAOAMAOBRAB9ANPC1TDP1 | |
| SCHEMBL30800165 | 0.85 | MAOA (0.55) | MAOAMAOBRAB9ANPC1TDP1 | |
| SCHEMBL6781940 | 0.79 | MAOA (0.50) | MAOAMAOBRAB9ANPC1TDP1 | |
| SCHEMBL7672328 | 0.79 | MAOA (0.53) | MAOAMAOBRAB9ANPC1TDP1 | |
| SCHEMBL7935368 | 0.77 | MAOA (0.51) | MAOAMAOBRAB9ANPC1TDP1 | |
| SCHEMBL254971 | 0.77 | ALDH1A1 (0.48) | MAOAMAOBRAB9ANPC1TDP1 | |
| SCHEMBL31568503 | 0.76 | MAOA (0.65) | MAOAMAOBRAB9ANPC1TDP1 | |
| SCHEMBL28524488 | 0.76 | MAOA (0.51) | MAOAMAOBRAB9ANPC1TDP1 | |
| SCHEMBL6522331 | 0.76 | MAOA (0.65) | MAOAMAOBRAB9ANPC1TDP1 | |
| SCHEMBL23430770 | 0.76 | ERN1 (0.57) | MAOAMAOBRAB9ANPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012033435-A1 | METHOD, COMPOUND, PHARMACEUTICAL COMPOSITION AND DRUG FOR RESTORING MEMORY LOST IN NORMAL AND PATHOLOGICAL CONTEXTS | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "БИОФАРМ-МЕМОРЕЙН" (RU) | 2012-03-15 | — | — | WO | disclosed |
| WO-2012030258-A1 | HETEROCYCLIC LOW-MOLECULAR SAPP MIMETICS, A PHARMACEUTICAL COMPOSITION AND METHODS FOR PRODUCING AND USING SAME | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "БИОФАРМ-МЕМОРЕЙН" (RU) | 2012-03-08 | — | — | WO | disclosed |