Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 9/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255358 | 0.88 | — | — | |
| SCHEMBL15235776 | 0.86 | — | — | |
| SCHEMBL158775 | 0.86 | — | — | |
| SCHEMBL253921 | 0.83 | CA2 (0.47) | ANPEPNPC1RAB9APPARG | |
| SCHEMBL1109169 | 0.83 | CA2 (0.47) | ANPEPNPC1RAB9APPARG | |
| SCHEMBL10272727 | 0.83 | CA2 (0.47) | ANPEPNPC1RAB9APPARG | |
| SCHEMBL1109123 | 0.83 | CA2 (0.47) | ANPEPNPC1RAB9APPARG | |
| SCHEMBL254790 | 0.83 | ANPEP (0.40) | ANPEP | |
| SCHEMBL1912162 | 0.81 | NPC1 (0.45) | ANPEPNPC1RAB9AMEN1LMNA | |
| SCHEMBL255253 | 0.78 | ANPEP (0.50) | ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012031298-A2 | ETHYNYLBENZENE DERIVATIVES | DUKE UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |