SCHEMBL25445486

SCHEMBL25445486

Cc1c(-c2c3sc4ccccc4c3cc[n+]2C)ccc2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.37
CYP1A2 P05177 1/20 0.36
CYP2A6 P11509 1/20 0.36
TSHR P16473 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.34
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 2/20 0.34
ATM Q13315 1/20 0.34
RAB9A P51151 1/20 0.34
GPR3 P46089 1/20 0.33
PARP14 Q460N5 1/20 0.33
LMNA P02545 2/20 0.32
ALOX5 P09917 1/20 0.32
HCRTR1 O43613 1/20 0.32
POLB P06746 1/20 0.32
MEN1 O00255 1/20 0.31
THRB P10828 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25445485 0.81 PARP14 (0.38) MAPTL3MBTL1ALDH1A1KDM4EATM
SCHEMBL25445480 0.80 TSHR (0.37) MAPTCYP1A2CYP2A6TSHRL3MBTL1
SCHEMBL25445414 0.78 TSHR (0.46) MAPTCYP1A2CYP2A6TSHRL3MBTL1
SCHEMBL25447983 0.77 HPRT1 (0.44) CYP1A2CYP2A6TSHRL3MBTL1ALDH1A1
SCHEMBL25446862 0.75 TSHR (0.42) MAPTCYP1A2CYP2A6TSHRL3MBTL1
SCHEMBL25446850 0.74 CYP1A2 (0.34) MAPTCYP1A2CYP2A6TSHRKDM4E
SCHEMBL25445493 0.72 CYP1A2 (0.40) MAPTCYP1A2CYP2A6TSHRL3MBTL1
SCHEMBL25446856 0.69 CYP2A6 (0.37) CYP1A2CYP2A6TSHRL3MBTL1ALDH1A1
SCHEMBL29903935 0.68 GPR3 (0.54) MAPTCYP1A2CYP2A6TSHRL3MBTL1
SCHEMBL1294668 0.68 GPR3 (0.54) MAPTCYP1A2CYP2A6TSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20230357296-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 US disclosed
EP-4265626-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-10-25 EP disclosed
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230337523-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230331757-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230337519-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230263049-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-08-17 US disclosed
US-11685754-B2 Heteroleptic organic electroluminescent materials UNIVERSAL DISPLAY CORPORATION (US) 2023-06-27 US disclosed
US-20230165134-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-25 US disclosed
US-20230144846-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 US disclosed
US-20230146148-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 US disclosed
US-11647667-B2 Organic electroluminescent compounds and organic light emitting devices using the same UNIVERSAL DISPLAY CORPORATION (US) 2023-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11685754-B2 Heteroleptic organic electroluminescent materials IK, ORC3, CACNA2D2 MAPT 1207/4885CYP1A2 1795/4885CYP2A6 3642/4885
US-20230146148-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ICOSLG MAPT 1448/4885CYP1A2 378/4885CYP2A6 1340/4885
US-20230144846-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OCIAD1, OCIAD2 MAPT 3608/4885CYP1A2 935/4885CYP2A6 2289/4885
US-11647667-B2 Organic electroluminescent compounds and organic light emitting devices using the same OCIAD1, OCIAD2, ODC1 MAPT 587/4885CYP1A2 421/4885CYP2A6 1474/4885
US-20230165134-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, TPO MAPT 574/4885CYP1A2 369/4885CYP2A6 3778/4885
US-20230357296-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, OXER1, LBR MAPT 4281/4885CYP1A2 1083/4885CYP2A6 3966/4885
US-20230337523-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OCIAD1, OCIAD2 MAPT 3762/4885CYP1A2 1850/4885CYP2A6 4021/4885
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, SSB, LBR MAPT 3654/4885CYP1A2 1701/4885CYP2A6 3909/4885
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP MAPT 1707/4885CYP1A2 1152/4885CYP2A6 3207/4885
US-20230263049-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBPL3, OCIAD1, OSBP MAPT 1710/4885CYP1A2 430/4885CYP2A6 1790/4885
US-20230331757-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, SSB, L1CAM MAPT 3633/4885CYP1A2 156/4885CYP2A6 2487/4885
US-20230337519-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SSB, YBX3, LBR MAPT 3321/4885CYP1A2 3467/4885CYP2A6 4513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.