Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.50 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.50 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371370 | 0.91 | ATM (0.59) | HSD11B1TP53ATMALDH1A1MEN1 | |
| SCHEMBL22940447 | 0.91 | ATM (0.59) | HSD11B1TP53ATMALDH1A1MEN1 | |
| SCHEMBL22602813 | 0.89 | HSD11B1 (0.70) | HSD11B1TP53ATMALDH1A1MEN1 | |
| SCHEMBL3952911 | 0.85 | HSD11B1 (0.70) | HSD11B1TP53ATMALDH1A1MEN1 | |
| SCHEMBL5517503 | 0.85 | HSD11B1 (0.70) | HSD11B1TP53ATMALDH1A1MEN1 | |
| SCHEMBL16365980 | 0.82 | MEN1 (0.48) | HSD11B1TP53ATMALDH1A1MEN1 | |
| SCHEMBL7217209 | 0.82 | TP53 (0.71) | HSD11B1TP53ATMALDH1A1MEN1 | |
| SCHEMBL4688026 | 0.81 | ATM (0.55) | HSD11B1TP53ATMALDH1A1MEN1 | |
| SCHEMBL2677070 | 0.81 | HSD11B1 (0.65) | HSD11B1TP53ATMALDH1A1MEN1 | |
| SCHEMBL4382097 | 0.80 | KMT2A (0.59) | HSD11B1TP53ATMALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230147312-A1 | TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME AND RELATED CONDITIONS WITH ANTAGONISTS OF E-SELECTIN | GLYCOMIMETICS, INC. (US) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230147312-A1 | TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME AND RELATED CONDITIONS WITH ANTAGONISTS OF E-SELECTIN | SELP, SELE, SELPLG | HSD11B1 1559/4885TP53 3997/4885ATM 1459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.