Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR3 | P25089 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CMA1 | P23946 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2541336 | 0.84 | FPR3 (0.34) | FPR3FPR2 | |
| SCHEMBL2541340 | 0.84 | FPR3 (0.34) | FPR3FPR2 | |
| SCHEMBL2544842 | 0.77 | FPR3 (0.34) | FPR3FPR2 | |
| SCHEMBL2546511 | 0.75 | PPARG (0.35) | CA1CA2CA7CA4CA9 | |
| SCHEMBL2544478 | 0.74 | PPARG (0.36) | FPR3FPR2CA1CA2CA7 | |
| SCHEMBL2551213 | 0.74 | CA1 (0.37) | CA1CA2CA7CA4CA9 | |
| SCHEMBL2548962 | 0.73 | PPARG (0.37) | CA1CA2CA7CA4CA9 | |
| SCHEMBL2548965 | 0.73 | PPARG (0.37) | CA1CA2CA7CA4CA9 | |
| SCHEMBL1743887 | 0.73 | OGA (0.36) | FPR3FPR2CA1CA2CA7 | |
| SCHEMBL2544472 | 0.71 | PPARG (0.38) | FPR3FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263647-A1 | FLUOROISOQUINOLINE SUBSTITUTED THIAZOLE COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263647-A1 | FLUOROISOQUINOLINE SUBSTITUTED THIAZOLE COMPOUNDS AND METHODS OF USE | TFEB, PCK2, JAK2 | FPR3 572/4885FPR2 277/4885CA1 3816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.