Oxirane

Oxirane

SCHEMBL2544975

C1CO1.OCC(O)C(O)CC1CO1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL182417 0.93 LMNA (0.35) LMNAL3MBTL1
Glycidol SCHEMBL27943413 0.87 MGAM (0.31) LMNAL3MBTL1
SCHEMBL4105257 0.83 ALDH1A1 (0.38)
SCHEMBL216985 0.82 TSHR (0.42)
Oxirane SCHEMBL11531139 0.80 ALDH1A1 (0.35) LMNA
SCHEMBL27482484 0.78 TDP1 (0.52) LMNAL3MBTL1
SCHEMBL4083765 0.78 TDP1 (0.52) LMNAL3MBTL1
Oxirane SCHEMBL3812959 0.78 ALDH1A1 (0.32) L3MBTL1
SCHEMBL5581614 0.76
SCHEMBL32684282 0.75 USP2 (0.40) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0173004-B1 VIBRATION ISOLATOR NISSHINBO INDUSTRIES, INC. (JP) 1989-02-22 EP claimed
CN-88105527-A Solvent-free manufacturing urethane vesicular structure and with fiber, fibrous material and other substrate composite methods 1988-12-28 CN claimed
US-4689357-A POLYETHERURETHANE NISSHIN SPINNING CO., LTD. (JP) 1987-08-25 US claimed
US-4652495-A Resilient coat for tie of direct-connection type track JAPANESE NATIONAL RAILWAYS (JP) 1987-03-24 US claimed
EP-0173004-A2 Vibration isolator NISSHINBO INDUSTRIES, INC. (JP) 1986-03-05 EP claimed
JP-2283711-A None JP disclosed
JP-2023097737-A MEASURING METHOD OF HMGB1 IN SPECIMEN AND MEASUREMENT REAGENT AND METHOD FOR SUPPRESSING NON-SPECIFIC AGGREGATION OF ANTI-HMGB1 ANTIBODY IMMOBILIZED CARRIER, AND METHOD FOR SUPPRESSING RISE OF REAGENT BLANK WHEN MEASURING HMGB1 IN SPECIMEN 株式会社シノテスト 2023-07-10 JP disclosed
CN-104072717-B Hard polyurethane foams with uniform cell size distribution and uniform open cell content 科思创德国股份有限公司 2018-04-17 CN disclosed
US-9777104-B2 Rigid polyurethane foams with high acoustic absorption COVESTRO DEUTSCHLAND AG (DE) 2017-10-03 US disclosed
EP-2439221-B1 EXPANDABLE POLYURETHANE COMPOSITION AND PROCESS FOR PRODUCTION OF POLYURETHANE FOAM MOMENTIVE PERFORMANCE MAT JP (JP) 2016-08-03 EP disclosed
US-9296856-B2 Rigid polyurethane foams with uniform cell size distribution and homogeneous open-cell content COVESTRO DEUTSCHLAND AG (DE) 2016-03-29 US disclosed
US-9266994-B2 Expandable polyurethane composition and manufacturing method of polyurethane foam MOMENTIVE PERFORMANCE MATERIALS JAPAN LLC (JP) 2016-02-23 US disclosed
US-4469653-A AS POLYMERIZATION CATALYSTS BASF AKTIENGESELLSCHAFT (DE) 1984-09-04 US disclosed
US-4463189-A ADDING 2,4-DIPHENYL-4-METHYL-2-PENTENE AND 2,4-DIPHENYL-4-METHYL-1-PENTENE HOECHST AKTIENGESELLSCHAFT (DE) 1984-07-31 US disclosed
US-4302552-A POLYETHERURETHANE FOAMS FROM POLYISOCYANATES, AND A CHAIN-EXTENDED ETHYLENE GLYCOL-PROPYLENE GLYCOL COPOLYMER; DAMPING NISSHIN SPINNING CO., LTD. (JP) 1981-11-24 US disclosed
US-4293657-A Stable melamine polyol dispersions, a process for their manufacture and for the preparation of foamed polyurethane plastics BASF AKTIENGESELLSCHAFT (DE) 1981-10-06 US disclosed
US-4145487-A Polyurethane foams containing reactive fibers and process for their manufacture HOECHST AKTIENGESELLSCHAFT (DE) 1979-03-20 US disclosed
US-4122035-A Process for reclaiming synthetic magnesium silicate or aluminum silicate adsorbents employed in the purification of polyether polyols BASF WYANDOTTE CORPORATION (US) 1978-10-24 US disclosed
US-4029879-A Process for the removal of catalysts from polyether polyols employing water and adsorbent BASF WYANDOTTE CORPORATION (US) 1977-06-14 US disclosed
US-4000065-A METHOD AND APPARATUS FOR PURIFYING AQUEOUS STREAMS CONTAMINATED WITH ORGANIC MATERIALS BASF WYANDOTTE CORPORATION (US) 1976-12-28 US disclosed