Oxirane

Oxirane

SCHEMBL3812959

C1CO1.CC(O)C(O)CC1CO1

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4291612 0.93
SCHEMBL7153740 0.79
Oxirane SCHEMBL2544975 0.78 LMNA (0.31) L3MBTL1
SCHEMBL4105257 0.78 ALDH1A1 (0.38) ALDH1A1
Oxirane SCHEMBL10908880 0.76
SCHEMBL7520510 0.76
SCHEMBL4983188 0.75 USP2 (0.40) ALDH1A1
SCHEMBL8442819 0.74
SCHEMBL193534 0.74
SCHEMBL669900 0.74 ALDH1A1 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014059593-A1 POLYURETHANE BASED SYNTHETIC LEATHERS COMPRISING NANOPARTICLES AND HAVING IMPROVED PEEL STRENGTH DOW GLOBAL TECHNOLOGIES LLC (US) 2014-04-24 WO claimed
WO-2014059597-A1 NANOPARTICLE CONTAINING POLYURETHANE DISPERSIONS AFFORDING MATERIALS HAVING IMPROVED TENSILE STRENGTH AND ELONGATION DOW GLOBAL TECHNOLOGIES LLC (US) 2014-04-24 WO claimed
EP-0173004-B1 VIBRATION ISOLATOR NISSHINBO INDUSTRIES, INC. (JP) 1989-02-22 EP claimed
US-4689357-A POLYETHERURETHANE NISSHIN SPINNING CO., LTD. (JP) 1987-08-25 US claimed
US-4652495-A Resilient coat for tie of direct-connection type track JAPANESE NATIONAL RAILWAYS (JP) 1987-03-24 US claimed
EP-0173004-A2 Vibration isolator NISSHINBO INDUSTRIES, INC. (JP) 1986-03-05 EP claimed
CN-118146384-A Anti-sclerostin constructs and uses thereof 安济盛生物医药有限公司 2024-06-07 CN disclosed
CN-115279787-B Anti-sclerostin constructs and uses thereof 安济盛生物医药有限公司 2024-06-07 CN disclosed
CN-118146382-A Anti-sclerostin constructs and uses thereof 安济盛生物医药有限公司 2024-06-07 CN disclosed
CN-118146383-A Anti-sclerostin constructs and uses thereof 安济盛生物医药有限公司 2024-06-07 CN disclosed
CN-118146385-A Anti-sclerostin constructs and uses thereof 安济盛生物医药有限公司 2024-06-07 CN disclosed
CN-118126189-A Anti-sclerostin constructs and uses thereof 安济盛生物医药有限公司 2024-06-04 CN disclosed
CN-118126190-A Anti-sclerostin constructs and uses thereof 安济盛生物医药有限公司 2024-06-04 CN disclosed
EP-0173004-B1 VIBRATION ISOLATOR NISSHINBO INDUSTRIES, INC. (JP) 1989-02-22 EP disclosed
US-4689357-A POLYETHERURETHANE NISSHIN SPINNING CO., LTD. (JP) 1987-08-25 US disclosed
US-4652495-A Resilient coat for tie of direct-connection type track JAPANESE NATIONAL RAILWAYS (JP) 1987-03-24 US disclosed
EP-0173004-A2 Vibration isolator NISSHINBO INDUSTRIES, INC. (JP) 1986-03-05 EP disclosed
US-4487609-A Powdered, stably dispersible, non-foaming dye formulations and process for their preparation CIBA-GEIGY CORPORATION (US) 1984-12-11 US disclosed
US-4293657-A Stable melamine polyol dispersions, a process for their manufacture and for the preparation of foamed polyurethane plastics BASF AKTIENGESELLSCHAFT (DE) 1981-10-06 US disclosed
US-4284524-A BUILDER, ALKALI METAL SILICATE, CHLORINE COMPOUND, NONIONIC SURFACTANT, POLYACETAL CARBOXYLATE THE PROCTER & GAMBLE COMPANY (US) 1981-08-18 US disclosed