Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20581597 | 0.86 | ALDH1A1 (0.44) | ALDH1A1CYP2C19LMNAKDM4EMAPT | |
| SCHEMBL20581598 | 0.86 | ALDH1A1 (0.44) | ALDH1A1CYP2C19LMNAKDM4EMAPT | |
| SCHEMBL18578806 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CYP2C19LMNAMAPTHPGD | |
| SCHEMBL2545175 | 0.80 | ALDH1A1 (0.45) | ALDH1A1CYP2C19LMNAKDM4EMAPT | |
| SCHEMBL4300636 | 0.80 | ALDH1A1 (0.46) | ALDH1A1CYP2C19LMNAMAPTSMN1; SMN2 | |
| SCHEMBL4300640 | 0.80 | ALDH1A1 (0.46) | ALDH1A1CYP2C19LMNAMAPTSMN1; SMN2 | |
| SCHEMBL29896503 | 0.79 | ALDH1A1 (0.56) | ALDH1A1CYP2C19LMNAKDM4EMAPT | |
| SCHEMBL29896531 | 0.78 | ALDH1A1 (0.52) | ALDH1A1CYP2C19LMNAMAPTPOLB | |
| SCHEMBL20581292 | 0.76 | ALDH1A1 (0.45) | ALDH1A1CYP2C19LMNAMAPTHTT | |
| SCHEMBL20581295 | 0.76 | ALDH1A1 (0.45) | ALDH1A1CYP2C19LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130203815-A1 | CYTOKINE INHIBITORS | Piramal Enterprises Limited (IN) | 2013-08-08 | — | — | US | disclosed |
| EP-2552886-A1 | CYTOKINE INHIBITORS | Piramal Healthcare Limited (IN) | 2013-02-06 | — | — | EP | disclosed |
| WO-2011121505-A1 | CYTOKINE INHIBITORS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130203815-A1 | CYTOKINE INHIBITORS | IL1B, IL1A, IL1R1 | ALDH1A1 517/4885CYP2C19 1217/4885LMNA 2464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.