SCHEMBL25452091

SCHEMBL25452091

c1ccc2c(c1)-c1c(Nc3ccc4oc5ccccc5c4c3)cccc1C21C2CC3CC(C2)CC1C3

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.33
HPGD P15428 11/20 0.33
ALDH1A1 P00352 10/20 0.33
KMT2A Q03164 10/20 0.33
MEN1 O00255 9/20 0.33
KDM4E B2RXH2 8/20 0.33
LMNA P02545 5/20 0.33
SMN1; SMN2 Q16637 5/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
DUSP3 P51452 1/20 0.32
GAA P10253 4/20 0.31
HTT P42858 3/20 0.31
NR1I2 O75469 1/20 0.31
AHR P35869 1/20 0.31
IDO1 P14902 1/20 0.31
CXCR3 P49682 1/20 0.31
SYK P43405 1/20 0.30
CYP1A2 P05177 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25452095 0.85
SCHEMBL25458192 0.82
SCHEMBL24728513 0.81 ALDH1A1 (0.36) MAPTHPGDALDH1A1KMT2AMEN1
SCHEMBL17777674 0.80 ALDH1A1 (0.39) MAPTHPGDALDH1A1KMT2AMEN1
SCHEMBL24728353 0.80 MEN1 (0.37) MAPTHPGDALDH1A1KMT2AMEN1
SCHEMBL22679968 0.79 HPGD (0.38) MAPTHPGDALDH1A1KMT2AMEN1
SCHEMBL22799310 0.78 SIRT2 (0.39) KMT2AMEN1SYKPOLBNPSR1
SCHEMBL25452127 0.78 SIGMAR1 (0.34) MAPTKMT2AMEN1KDM4EGAA
SCHEMBL24728445 0.78 SIGMAR1 (0.34) MAPTKMT2AMEN1KDM4EGAA
SCHEMBL23959398 0.78 MAPK14 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230146030-A1 ARYLAMINE COMPOUND, ELECTRONIC COMPONENT USING SAME AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-05-11 US disclosed
US-20230146030-A1 ARYLAMINE COMPOUND, ELECTRONIC COMPONENT USING SAME AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230146030-A1 ARYLAMINE COMPOUND, ELECTRONIC COMPONENT USING SAME AND ELECTRONIC DEVICE OCIAD2, AOC2, OCIAD1 MAPT 3021/4885HPGD 1997/4885ALDH1A1 442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.