Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30639141 | 0.90 | ALDH1A1 (0.43) | DHFREGFRALDH1A1CYP3A4TDP1 | |
| SCHEMBL6754283 | 0.80 | L3MBTL1 (0.46) | ALDH1A1KDM4ECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL22453529 | 0.78 | ALDH1A1 (0.33) | DHFRALDH1A1CYP3A4TDP1TP53 | |
| SCHEMBL30488787 | 0.78 | GBA1 (0.50) | DHFREGFRALDH1A1KDM4EMAPT | |
| SCHEMBL25301327 | 0.78 | GBA1 (0.50) | DHFREGFRALDH1A1KDM4EMAPT | |
| SCHEMBL28504853 | 0.77 | HDAC6 (0.49) | DHFREGFRALDH1A1CYP3A4TDP1 | |
| SCHEMBL29618352 | 0.76 | ALDH1A1 (0.42) | ALDH1A1CYP3A4TDP1KDM4ETP53 | |
| SCHEMBL142308 | 0.76 | ALDH1A1 (0.42) | ALDH1A1CYP3A4TDP1KDM4ETP53 | |
| SCHEMBL12016060 | 0.75 | KDM4C (0.44) | DHFREGFRTDP1KDM4EMAPT | |
| SCHEMBL5206210 | 0.74 | CYP2D6 (0.44) | DHFREGFRALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2671575-A1 | Ras inhibitors | Universität Regensburg (DE) | 2013-12-11 | — | — | EP | claimed |
| WO-2023081800-A1 | ALPHA-2A ADRENERGIC RECEPTOR MODULATORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-05-11 | — | — | WO | disclosed |
| EP-2671575-A1 | Ras inhibitors | Universität Regensburg (DE) | 2013-12-11 | — | — | EP | disclosed |